10 most important medicines in history and their Discoverers
1. Penicillin – discovered in 1928
Alexander Fleming
2. Insulin – discovered in 1921
Charles Best and Frederick Grant Banting
3. Aspirin – discovered in 1899 By pharmacist of Bayer
4. Smallpox vaccine – discovered in 1798
By Edward Jenner and Sarah Nelmes
5. Morphine – Morphine was first discovered in 1804 by German pharmacist Friedrich Serturner
6. Ether – discovered in 1842 Crawford Williamson Long
7. Chemotherapy drugs – discovered in 1956, by Roy Hertz and Min C. Li, uncovered methotrexate
8. HIV protease inhibitors – discovered By  1989 Hoffmann-LaRoche Inc, Abbot and Merck
9. Botox – discovered in 1978 By
Alan B. Scott
10. Warfarin – discovered in 1933
DRUGS OF CHOICE
1. Algia(pain)/pyrexia– Paracetamol
2. Acute bronchial- asthma :- salbutamol
3. Acute gout :- NSAIDS
4. Acute hyperkalemia:– calcium gluconate
5. Severe DIGITALIS toxicity :-DIGIBIND
6. Acute migraine :- sumatriptan
7. Cheese reaction :- phentolamine
8. Atropine poisoning :- physostigmine
9. Cyanide poisoning :- amyl nitrite
10. Benzodiazepine poisoning:- flumazenil
11. Cholera :- tetracycline
12. KALA-AZAR :- lipozomal amphotericin- B
13. Iron poisoning :- desferrioxamine
14. MRSA :- vancomycin
15. VRSA :- LINEZOLID
16. Warfarin overdose :- vitamin-K
17. OCD :- fluoxetine
18. Alcohol poisoning :- fomepizole
19. Epilepsy in pregnency :- phenobarbitone
20. Anaphylactic shock :- Adrenaline
21. MRSA Infection – Vancomycin
22. Malaria in Pregnancy – Chloroquine
23. Whooping Cough or Perteusis – Erythromycin
24. Kawasaki disease – IV
25. Warfarin Overdose – Vit-K
