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Industrial pharmacy MCQs with Answers

MULTIPLE CHOICE QUESTIONS With Answers

1. According to USP, Sparingly soluble means the Parts of solvent required for one part of
solute is
a) 30-100
b) 10-30
c) 100-1000
d) Less than 1

2. At a specified temperature, maximal amount of solute that can dissolve in an amount of solvent is known as
a) Solubility
b) Dissolution
c) Diffusion
d) Capacity

3. PH of the solution depends on
a) HENDERSON-HASSELBALCH equation
b) Henry’s Law
c) Charle’s law
d) Dalton’s Law

4. The ratio of void volume to bulk volume is known as
a) Bulk density
b) Tapped density
c) Porosity
d) Granule volume

5. Hausner Ratio is
a) Tapped density / Bulk density
b) Bulk density / Tapped density
c) Bulk volume / Void volume
d) Void volume / Bulk volume

6. _______ is the ratio of the mean residence time to the absorption time
a) Absorption number
b) Dissolution number
c) Dose number
d) Intrinsic dissolution

7. According to Biopharmaceutics Classification System (BCS), Class II drugs have
a) High solubility/High permeability
b) Low solubility /High permeability
c) High solubility /Low permeability
d) Low solubility /Low permeability

8. Accelerated stability testing is done to
a) Predict shelf of the formulation
b) Predict dissociation constant
c) Predict diffusion constant
d) Determine activation energy

9. Stability testing is done
a) To determine shelf life of product
b) To determine the components used for packaging
c) To get information at preformulation stage
d) All of the above

10. Which of the following tablet are formulated to prevent drug release in stomach?
a) Enteric coated tablet
b) Film coated tablet
c) Sugar Coated tablet
d) Chewable tablet

11. Which of the following tablet is also called as ball’s-eye tablet
a) Sugar Coated tablet
b) Chewable tablet
c) Inlay Tablet
d) Lozenges

12. Which of the following table placed under the tongue to dissolve?
a) Sublingual tablet
b) Buccal tablet
c) Lozenges
d) Troches

13. Which of the following is not used as diluents?
a) Lactose
b) Microcrystalline cellulose
c) Calcium Carbonate
d) Poly Vinyl Pyrrolidone

14. Tablet are coated
a) To protect the drug from the external environment
b) To mask bitter tastes
c) To make swallowing easier
d) All of the above

15. Why tragacanth is not used as binder because it
a) Harden on storage
b) Require in large amount
c) Incompatible with most of the drugs
d) Suitable in warm condition

16. Dried corn starch is mixed with granules for purpose of
a) Lubrication
b) Disintegration
c) Whiteness
d) Binder

17. Adhesion of tablet material to die wall is called
a) Mottling
b) Sticking
c) Picking
d) Capping

18. If the average weight of tablet 300mg, then allowed weight variation is
a) 10%
b) 7.5%
c) 5%
d) 1%

19. To assess the resistant of tablet to abrasion, the test performed is known as
a) Hardness test
b) Disintegration test
c) Friability test
d) None of the above

20. For sugar coated tablet, specified disintegration time is
a) 5 minutes
b) 30 minutes
c) 60 minutes
d) 120 minutes

21. Ordinary tablet posess hardness of
a) 2 kg/cm2
b) 4 kg/cm2
c) 5 kg/cm2
d) 1 kg/cm2

22. Which of the following method preferably prepared for manufacturing of Aspirin?
a) Direct compression
b) Wet granulation
c) Dry granulation
d) Both a & c

23. Cam tracks are used in tablet for
a) Feeding the granules
b) Adjusting shape
c) Guiding movement of punches
d) Compress the granules

24. In the dry granulation method of tablet manufacturing, slugging is carried out by
a) Oscillating granulation
b) Hammer mill
c) Chilsonator roller compactor
d) Fluidized bed granulator

25. Subcoating is given to tablets
a) To increase size of tablet
b) To avoid deterioration due to microbial attack
c) To prevent solubility in acidic medium
d) To avoid stickiness

26. For stable emulsion phase volume ratio is
a) 52/48
b) 26/74
c) 74/26
d) 48/52

27. In emulsion distribution of globules is not uniform in emulsion. This stage is called
a) Caking
b) Creaming
c) Breaking
d) Coalescence

28. On commercial scale emulsion is prepared by
a) Homogenization
b) Dialysis
c) Freezing
d) Centrifugation

29. In Dry gum method, 4:2:1 consist of
a) 4 parts oil, 2 parts water, and 1 part emulsifier
b) 4 parts water, 2 parts oil, and 1 part emulsifier
c) 4 parts emulsifier, 2 parts water, and 1 part emulsifier
d) 4 parts oil, 2 parts emulsifier and 1 part water

30. Dry Gum Method is also known as
a) Continental method.
b) English method
c) Bottle method
d) Forbe’s method

31. Draughts contain
a) 5 doses
b) 1-3 doses
c) 10 doses
d) 7 doses

32. Which of the following is a sweet, sticky preparation with medicaments to exert a local action on the mucous membrane of the throat
a) Linctus
b) Draught
c) Lotion
d) Liniment

33. Which of the following are the desired features of good suspension:
a) The particles which settle down should not deposit at the bottom as hard cake. They must be easily re-suspended by moderate shaking.
b) It should be free from grittiness.
c) It should be stable in case of physical chemical and microbial attack.
d) All of the above

34. The ratio of the ultimate volume of sediment to the actual volume of sediment before settling is called
a) Sedimentation volume
b) Degree of flocculation
c) Emulsification volume
d) Phase volume ratio

35. The ability of a substance dissolves in a given solvent system is depends on
a) Nature and intensity of the forces present in the solute
b) Nature and intensity of the forces present in the solvent
c) Solute-Solvent Interaction
d) All of the above

36. Dimethyl acetamide is not been used as a co-solvent in oral liquids
a) Due to objectionable odor
b) Due to objectionable taste
c) Both a and b
d) None of the above

37. Which of the following is a type of capsule
a) Hard gelatine
b) Soft gelatine
c) Both a and b
d) Layered capsule

38. Smallest size of capsule most widely used is
a) 0
b) 5
c) 1
d) 000

39. Erweka KEA is used in capsule manufacturing or processing
a) As weighing machine
b) To fill pellets into capsules
c) To remove unfilled or unjoined joined capsule
d) For dusting and polishing of capsules

40. Capsule no “0” has capacity of
a) 250 mg
b) 450 mg
c) 100 mg
d) 650 mg

41. Sulphur dioxide is used in gelatine preparation
a) As colouring agent
b) To prevent decomposition
c) To reduce bitterness
d) All of the above

42. Isoelectric point of Type A gelatine is
a) Between 7 and 9
b) 10
c) Between 4.7 and 5.3
d) Between 12 and 15

43. Disintegration time of soft capsule is
a) 60 minute
b) 15 minute
c) 30 minute
d) 5 minute

44. Basic empty capsule shell are made from a mixture of
a) Sugar
b) Water
c) Gelatine
d) All of the above

45. Which of the following is the states of nucleation phase?
a) Pendular
b) Funicular
c) Capillary
d) All of the above

46. Ball growth phase is also known as
a) Abrasion transfer phase
b) Coalescence phase
c) Layering phase
d) Nucleation phase

47. Which of the following is not pelletization process?
a) Agitation
b) Compaction
c) Sieving
d) Globulation

48. The process in which liquid droplet is converted into solid spherical particle by using liquid nitrogen is called
a) Cryopelletizatiay
b) Peptization
c) Microscapsulation
d) Spheronization

49. Which of the following can be used as solvent for parenterals
a) Dimethyl acetamide
b) PEG 400
c) Benzyl benzoate
d) All of the above

50. An injection inserted directly into artery is known as
a) Intra-arterial
b) Inter-arterial
c) Extra arterial
d) Intravenous

51. Vehicle for parenteral preparation which also posess antioxidant activity
a) Ethanol
b) Sesame oil
c) Olive oil
d) Cotton seed oil

52. Which of the following used as stabilizer in parenteral dosage form?
a) Acetates
b) Tetrasodium edentate
c) Creatinine
d) Benzyl alcohol

53. Most commonly used antimicrobial agent for intraperitoneal dialysis fluid is
a) Chlorocresol
b) Benzalkonium chloride
c) Alcohol
d) None of the above

54. Which of the following is used as Bulking agent for parenteral preparations
a) Sorbitol
b) Carbolic acid
c) Benzyl alcohol
d) Benzoic acid

55. Thiomersal is used in parenteral products as
a) Buffer
b) Antimicrobial agent
c) Antioxidant
d) Chelating agent

56. The pyrogenic activity of pyrogens is associated with
a) O-antigenic side chain
b) Lipid A portion
c) Central polysaccharide
d) All of the above

57. How much concentration of Benzalkonium chloride is used as preservative in eye drop ?
a) 10% w/v
b) 0.05% w/v
c) 0.01% w/v
d) 1% w/v

58. The direction “To be used within 30 days after first opening.” is given for ______
a) Suppositories
b) Mixture
c) Paste
d) Eye drops

59. In eye drops, thickening agent is used to
a) Prolong contact with eye
b) Wash eyes
c) Lubricate contact lens
d) None of these

60. Concentration of solids in ophthalmic suspension should be
a) Less than 10%
b) Less than 30%
c) Less than 5%
d) Less than 15%

61. Which of the following is used as vehicle in ophthalmic drops
a) Ethanol
b) Methanol
c) Isopropyl alcohol
d) Boric acid

62. Which of the following is used as preservative in ophthalmic preparations?
a) Benzalkonium chloride
b) Phenol
c) Benzoic acid
d) Chlorocresol

63. Lip gloss in
a) Liquid lipstick used to colour lips
b) Adhering liquid
c) Liquid that give shine to lips
d) Lipstick used to protect lips from dry weather

64. The role of Zinc pyridinium thiol N-oxide in shampoos as
a) Surfactant
b) Conditioning agent
c) Preservatives
d) Anti-dandruff agent

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65. Which is not true for good lipstick
a) It should melt at body temperature
b) It should be smooth and easy to apply
c) It should have high retention for colour
d) It should have pleasant odor and test

66. Which of the following mainly contain Titanium dioxide
a) Cold cream
b) Suncream
c) Moisturizing cream
d) All of the above

67. Which of the following ingredient in vanishing cream is used for giving white shining appearance
a) Stearic acid
b) Beeswax
c) Borax
d) Potassium hydroxide

68. Which of the following in the vanishing cream is used for its emollient effect
a) Stearic acid
b) KOH
c) Glycerin
d) Cetyl alcohol

69. Percentage of oily phase in vanishing cream is
a) 50 %
b) 20-25 %
c) 40-60 %
d) 10-15 %

70. Texture of Vanishing Creams depends on
a) Amount of stearic acid
b) Amount of Surfactants
c) Amount of stearic acid & alkali
d) Amount of Alkali

71. Which of the following is most effective sunscreen?
a) PABA
b) Titanium dioxide
c) Ferric oxide
d) Menthyl salicylate

72. 4-methyl-7-diethylamine coumarin is used as ________ in shampoo
a) Pearlescent agent
b) Conditioning agent
c) Surfactants
d) Sequestrants

73. Which of the following propellant used for topical pharmaceutical aerosols?
a) Trichloro monofluoro methane
b) Propane
c) Dichloro difluoro methane
d) Dichloro tetra fluoro ethane

74. Which apparatus is used to determine flash point of aerosal products
a) Coulter counter
b) Tag open cup apparatus
c) Rheometer
d) Osmometer

75. Vapour pressure of propellant for aerosol are calculated from
a) Boyal’s law
b) Fick’s law
c) Stoke’s law
d) Dalon’s law

76. Functioning of actuator is
a) Convey liquid from bottom
b) Easy opening and closing of valve
c) Propel the content
d) None of these

77. Size of suspended particles in aerosol products ideally range from
a) 200-250 μ
b) 20-25 μ
c) 0.5-4 μ
d) 150-200 μ

78. Storage condition for pharm aerosol is
a) Below 120°F
b) Below 90°F
c) Below 10°F
d) Below 100°F

79. The term PSIG in reference to aerosols means
a) Propellant safety in glass
b) Pounds per square inch gauge
c) Per square inch of glass
d) Atmospheric pressure

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80. Diptube of aerosol container is made from
a) Polypropylene
b) Glass
c) Stainless steel
d) Aluminium

81. In aerosol regulation of dose is concerned with
a) Propellant
b) Actuator
c) Metered valve
d) Dip tube

82. Which one of the following device is used to increase efficiency of drug delivery via aerosols
a) Tube spacer
b) Metered valve
c) Actuator
d) Pressure valve

83. The container used to protect the product from contamination and as well as from loss of contents during use are called
a) Well-closed containers
b) Air tight containers
c) Light-resistance containers
d) Multiple dose containers

84. Type III glass is also known as
a) Soda lime glass
b) General purpose soda lime glass
c) Borosilicate glass
d) Treated Soda Lime glass

85. Which of the following is used as Vulcanizing agent in manufacture of rubber closure?
a) Sulphur
b) Activated carbon black
c) Talc
d) Stearic acid

86. The package composed of base layer having cavities which hold the pharmaceutical product and a lid is called
a) Strip Package
b) Child resistant package
c) Blister Package
d) Well closed package

Other Part Links

➡️ Industrial pharmacy MCQs with Answers :- Click here

➡️ Industrial pharmacy:- 1 MCQs with Answers :- Click here

➡️ INDUSTRIAL PHARMACY–I (BP605TP) MCQs with Answers :- Click here

➡️ Industrial pharmacy–I (BP605TP) (Part:- 2) MCQs with Answers :- Click here

➡️ Industrial pharmacy–I (BP605TP) (Part:- 3) MCQs with Answers :- Click here

➡️ Industrial pharmacy–I (BP605TP) (Part:- 4) MCQs with Answers :- Click here

Subject:- Industrial pharmacy MCQs

Semester:- 6th sem , sem 6

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