Technology (IMP) GTU
Ch-1 Tablets
Q.1) Define and classify Tablet. Write a note on soluble Tablets.
Q.2) Describe film coating defects in tablets with remedies.
Q.3) Explain in brief compression and compaction of tablets.
Q.4) Write a note on Tablet compression Tooling.
Q.5) Discuss in-process quality control tests of tablets.
Q.6) Explain in brief capping and lamination defects of tablets.
Q.7) Write objectives of coating. Discuss various film forming materials.
Q.8) Write a note on Matrix tablet.
Q.9) Define Compressed tablet. Give advantages and disadvantages of tablet.
Q.10) Explain mouth dissolving tablets in brief.
Q.11) Describe excipients of tablets ; give at least two brand name of each.
Q.12) Explain in detail about evaluation of tablets.
Q.13) What are types of tablet coating? Write a note on equipment for coating of tablets.
Q.14) What are objectives of enteric coating? Describe polymers used for enteric coating.
Q.15) Define Tablet. Give Classification of Tablets. Write a note on sizes of Tablets.
Q.16) Write a note on excipients of compressed tablets.
Q.17) What are IPQC & final evaluation parameters for mouth dissolving and colon targeted tablets?
Q.18) Write a note on use and care of Tablet tooling.
Q.19) Discuss different granulation technique for tablets.
Ch-2 Capsules
Q.20) What is hard gelatin capsule? Give comparative advantages & disadvantages of Capsules over Tablets. Write a note on IP Capsules.
Q.21) What is difference between micro capsules and micro spheres?Write a note on application on biodegradable and non-biodegradable polymers used in that.
Q.22) Write a note on Air suspension technique.
Q.23) Compare hard gelatin capsules with soft gelatin capsules.
Q.24) Write a note on IPQC for capsules with special emphasis on dissolution testing.
Q.25) What is cross linking problem in gelatin capsule cells?
Q.26) Describe biodegradable and non-biodegradable polymers used in
microcapsules.
Q.27) Differentiate terms microcapsule and microspheres. Discuss in detail coacervation phase phenomena.
Q.28) Write a short note on characterization of microspheres.
Q.29) Discuss formation of soft gelatin capsule shell.
Q.30) Discuss different formulation problems and remedies thereof for filling hard gelatin capsules.
Q.31) Enumerate the techniques of microencapsulation. Describe working of
“Wurster Apparatus”.
Q.32) Describe rotary die process of manufacturing soft gelatin capsules with schematic diagram.
Q.33) Discuss importance of climatic control in capsule department.
Ch-3 Extrusion and Pelletization.
Q.34) What is Pelletization? Discuss factors affecting pellet properties.
Q.35) Discuss factors affecting pellet properties. Write Melt extrusion method of pellet preparation.
Q.36) Discuss applications of Extrusion in p’ceutical field.
Q.37) Explain extrusion and pelletization & describe equipment used for it.
Q.38) What is role of polyethylene oxide, Eudragit and MCC in extrusion and pelletization?
Q.39) Write a note on ready to use pellets available in market.
Q.40) Write a note on excipients used in pellets.
Ch-4 Supercritical fluids
Q.41) Describe preparation method of powder from liquid by using supercritical fluids.
Q.42) Explain phase diagram with labeled sketch shows supercritical region with examples.
Q.43) Write p’ceutical applications of supercritical fluid.
Q.44) Discuss equipment for super critical fluid processing.
Ch-5 Pharmaceutical Packaging
Q.45) Write a short note on evaluation tests of p’ceutical packaging materials.
Q.46) Discuss regulatory requirements in packaging.
Q.47) Define packaging. Discuss types of packaging.
Q.48) Discuss different methods for evaluation of packaging.
Q.49) Write a note on different types of packaging material.
Q.50) Write a note on influence of packaging components on dosage form stability.
Q.51) Differentiate Primary and secondary packaging with examples.
Q.52) What is temper evident conatiners and closures?
