Description
Antibiotics
β-lactam Antibiotics
• β-lactam antibiotics – penicillins – History
• Structure and properties of penicillin
• Structure and activity relationships of penicillins
• Sensitivity of penicillins – due to acid, β-lactamase
• Narrow spectrum of activity of penicillins
• Extended (broad) spectrum Penicillins
• Discuss the structure and properties of Penicillins
• Explain the SAR of penicillins
• Explain the sensitivity of penicillins towards acid and enzymes
• Describe the causes for narrow spectrum of activity of Penicillins
• Discuss the structural modifications to design extended spectrum of penicillins
• β-lactam antibiotics – penicillins – History
• Structure and properties of penicillin
• Structure and activity relationships of penicillins
• Sensitivity of penicillins – due to acid, β-lactamase
• Narrow spectrum of activity of penicillins
• Extended (broad) spectrum Penicillins
Unit:- 1
MEDICINAL CHEMISTRY – III
- Subject:- Medicinal chemistry 3
- Course:- B.pharm (pharmacy),
- Semester:- 6th sem , sem :- 6
