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Adverse Effect Of Loop Diuretics

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ADVERSE EFFECT OF LOOP DIURETICS

OH MAy GoD NoH

O – Ototoxicity
H – Hypokalemia, Hypocalcemia , Hypotension
M – Metabolic alkalosis
A – Arrhythmia
G – Gout
D – Dehydration
N – Nephritis
H – Hyperglycemia

IMMEDIATE TREATMENT OF MI

MONA

M – Morphine
O – Oxygen
N – Nitroglycerin
A – Aspirin(to prevent progression of clot)

WHO AM I

My characteristics are

???? Preferred as ORAL ANTICOAGULANT

???? I am inhibiting the synthesis of CLOTTING FACTOR II, VII , IX , & X

???? My S- ISOMER is most active

???? I am mainly Metabolizes by CYP2C9

???? My Toxicity can be reversed by VITAMIN K

???? NSAIDs , Allopurinol , Macrolides, Alcohol, Phenytoin, Omeprazole Citalopram *INCREASES MY ACTION*

???? Barbiturate, Oral contraceptive , Rifampin Griseofulvin DECREASES MY ACTION

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