Antibody Notes 6th sem
~Antibody is a type of protein called gamma globulin
~gamma shaped
~4 polypeptide chain molecule
(2 light & 2 heavy polypeptide )
~Antibodies are classified into 5 types:-
(1)IgD
(2)IgG(1st Major)
(3)IgA(2nd major)
(4)IgM
(5)IgE
Details of IgD:-
———————–
Molecular wt.:-1,80,000 Daltons
Half life:-3 days
Serum concentration:-0.03 mg/ml
Physical State:-Monomer
Main Function:- Not known.
Details of IgG:-
———————–
Molecular wt.:-1,50,000 Daltons
Half life:-21 days
Serum concentration:-12 mg/ml
Physical State:-Monomer
Main Function:- Protects the body fluid.
Details of IgA:-
———————–
Molecular wt.:-1,60,000 Daltons
Half life:-6 days
Serum concentration:- 2 mg/ml
Physical State:-Monomer/Di/Polymer
Main Function:- Protects the body surface.
Details of IgM:-
———————–
Molecular wt.:-9,00,000 Daltons
Half life:-5 days
Serum concentration:-1.2 mg/ml
Physical State:-Pentamer
Main Function:- Protects the blood stream.
Details of IgE:-
———————–
Molecular wt.:-1,85,000 Daltons
Half life:-2 days
Serum concentration:-0.0004 mg/ml
Physical State:-Monomer
Main Function:- Mediates Type 1 hypersentivity.
