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GPAT Practice MCQs (Part:- 13)

GPAT Practice MCQs with Answer

1️⃣ Which of the following compound will be oxidised by CrO3 in acid ?
(a)4-Methylcyclohexene
(b)3-Methyl,3-hydroxyclohexanone
(c)4,4-Dimethyl-1-methyl-1,3-cyclohexandiol
(d) 2-Methylcyclohexanone

2️⃣ Which of the following compounds absorbs at the longest wavelength
(a) 1,3,5-Hexatriene
(b) 1,3,5,7-Octatetraene
(c)1,7-Diphenyl-1,3,5-heptatriene
(d)1,6-Diphenyl-1,3,5-heptatriene

3️⃣ Which of the following reagents will reduce a disubstituted alkyne to trans-alkene
(a) Na and NH3
(b) LiAlH4
(c) B2H6
(d) Pd and H2

4️⃣ If the pKa of lidocaine is 7.9 and pH of the infected tissue is 8.9, the fraction of drug in the ionized form will be
(a) 10% (b) 1%
(c) 90% (d) 99%

5️⃣ Which among the following are the salient features of Glucocorticoids
(a) Gets combined with highly specific cytosolic glucocorticoids
(b) They promote phagocytosis by macrophages
(c) Releases of lytic enzymes
(d) Increases lipid eicosanoids and prostaglandin gene

6️⃣ Geometrical isomerism is possible in case of:
(a) 2-Pentene (b) Pentane
(c) Propene (d) Ethene

7️⃣ The loading dose (DL) of a drug is usually based on the:
(a) Total body clearance of the drug
(b) Percentage of drug bound to plasma proteins
(c) Fraction of drug excreted unchanged in the urine
(d) Apparent volume of distribution & desired drug concentration in plasma

8️⃣ Biologically active arachidonic acid is
(a) All transeicosatetraenoic acid
(b) All cis eicosatetraenoic acid
(c) All transeicosatrienoic acid
(d) All cis eicosatrienoic acid

9️⃣ Antidiabetic action of gliburidestart at molecular level by which mechanism ?
(a) Phosphorylation of receptor
(b) Binding to potassium ions
(c) Decrease in potassium effiux
(d) Increase in potassium effiux

???? Momordica charantia having blood sugar lowering activity due to:
(a) Momordicin
(b) Charantin
(c) Momortin
(d) Charantiamarin

Answers

1-C ( 4,4 dimethyl 1 methyl 1,3 cyclohexandiol )
2-D ( 1,6 diphenyl 1,3,5, heptatriene )
3 A ( Na and Nh3)
4-C ( 90% )
5-A ( Gets combined with highly specific cytosolic glucocorticoid )
6-A ( 2 pentene )
7-D ( Apparent volume of distribution & desired drug concentration in plasma )
8 B ( All cis eicosatetraenoic acid )
9-C( Decrease in potassium effiux )
10. B ( Charantin )

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