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Lipid-Lowering Drugs MCQs With Answers

Lipid-Lowering Drugs MCQs Question bank

1. Elevated plasma triglycerides in the absence of elevated cholesterol is
a. hyperlipemia.
b. hyperlipoproteinemia.
c. cerebrovascular disease.
d. peripheral vascular disease.

2. Atherosclerosis develops predominantly in which vessels?
a. Veins.
b. Capillaries.
c. Post-capillary venules.
d. Medium to large arteries.

3. Which class of lipoprotein has the highest lipid content?
a. Low-density lipoprotein (LDL).
b. High-density lipoprotein (HDL).
c. Very-low-density lipoprotein (VLDL).
d. Intermediate-density lipoprotein (IDL).

4. Low-density lipoproteins comprise which percentage of blood’s total plasma cholesterol?
a. 25%.
b. 40%.
c. 60%.
d. 75%.

5. Excretion of cholesterol from the body is accomplished by which means?
a. Urine.
b. Feces.
c. Breath.
d. Perspiration.

6. Which is considered the cornerstone of treatment for hyperlipidemias?
a. Prescription of a single antihyperlipidemic drug.
b. Prescription of a combination of antihyperlipidemic drugs.
c. Over-the-counter remedies, like nicotinic acid and omega-3 fatty acids.
d. Nonpharmacologic remedies, like a low-fat diet, exercise, and smoking cessation.

7. Which drug group acts by increasing both the catabolism of very-low-density lipoproteins (VLDLs) and biliary excretion?
a. Nicotinic acid.
b. Bile acid sequestrants.
c. Fibric acid derivatives.
d. Cholesterol absorption inhibitors.

8. Other lipid-lowering agents do not produce which nicotinic acid-related adverse effect?
a. Nausea.
b. Diarrhea.
c. Flushing.
d. Abdominal pain.

9. Which drug is a bile acid sequestrant?
a. Clofibrate.
b. Pravastatin.
c. Gemfibrozil.
d. Colesevelam.

10. Which lipid-lowering drug group is contraindicated for use in patients with coronary artery disease?
a. Thyroid-active drugs.
b. Cholesterol absorption inhibitors.
c. HMG-CoA reductase inhibitors (statins).
d. Omega-3 polyunsaturated fatty acids (PUFAs).

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