MICROBIOLOGY-3
1. Which of the following is called serum Hepatitis?
a. HCV
b. HAV
c. HBV
d. HIV
2. Which of the following was a non-neural vaccine for rabies?
a. HEPV
b. Card vaccine
c. BPL
d. Simple
3. Which type of antibodies will associate in blood cell coagulation?
a. IgE
b. IgA
c. IgM
d. IgG
4. In a antigen haptens are
a. Immunogenic
b. Non-immunogenic
c. Antigenic
d. None of these
5. The antibody that is first formed after infection is
a. IgG
b. IgM
c. IgD
d. IgE
6. Antibodies in our body are produced by
a. B-lymphocytes
b. T-lymphocytes
c. Monocytes
d. RBC’s
7. The points at which crossing over has taken place between homologus chromosomes are called
a. Chiasmata
b. Synaptonemal complex
c. Centromeres
d. Protein axes
8. How much globulin present in human serum?
a. 8%
b. 12%
c. 16%
d. 4%
9. The substance which acts as antimetabolites are called
a. Activators
b. Substrates
c. Inhibitor
d. Cofactor
10. Enzymes are chemically
a. Lipids
b. Proteins
c. Carbohydrates
d. None of these
11. Monoclonal antibodies are produced by
a. Hybridoma technology
b. Biotechnology
c. Fermentation Technology
d. None of these
12. First line of body defence is
a. Antibody molecules
b. Unbroken skin
c. Antigen molecules
d. Phagocytic cells
13. What is the strength of the bond between antigen and antibody?
a. Affinity
b. Avidity
c. Covalent
d. None of these
14. Syphillis is caused by
a. Staphylococcus aureuss
b. Yersinia psdtis
c. Treponema pallidum
d. Streptococcus syphilitis
15. Nergibodies produced by rabies virus show characteristic _____ inner granues?
a. Basophilic
b. Eosinophilic
c. Neutrophilic
d. Acidophilic
16. The widely used yeast for the production of single cell protein is
a. Saccharomyces cerevisiae
b. Rhizopus
c. Candida utilis
d. All of the above
17. Analysis of protein antigen is by
a. Southern blot
b. Northern blot
c. Western blot
d. None of these
18. Which of the following can provide naturally acquired passive immunity for the new born.
a. IgA
b. IgG
c. IgE
d. IgM
19. AIDS disease is caused by a virus which belongs to
a. Retro virus group
b. Rhabdo virus group
c. Hepatitis virus group
d. Adeno virus group
20. Complement based agglutination reaction is known as
a. Haem agglutination
b. Coplement fixation
c. Conglutination
d. Schultz Dale Phenomenon
21. Reverse transcriptase is an enzyme involved in the synthesis of
a. DNA
b. Soluble RNA
c. m-RNA from DNA
d. Nucleotides
22. The cellular immune response is mediated by
a. B cells
b. T cell
c. BT cells
d. Endothelial cells
23. The major immunoglobulin present in the human serum is
a. IgG
b. IgA
c. IgE
d. IgG
24. Reagenic type antibody is
a. IgG
b. IgA
c. IgM
d. IgE
25. Blood group antigens are
a. Species specific
b. Isospecific
c. Autospecific
d. Organ specific
26. The reaction of soluble antigen with antibody is known by
a. Precipitation
b. Flocculation
c. Agglutination
d. Complement fixation
27. Interferon is composed of
a. Lipids
b. Lipoprotein
c. Glycoprotein
d. Nucleic acid
28. Agglutination reaction is strongest with the immunoglobulin:
a. IgM
b. IgG
c. IgA
d. IgD
29. The use of monoclonal antibodies is
a. Immunotherapy
b. Gene therapy
c. Blood transfusion
d. Organ transfusion
30. Hybridoma technique is used for
a. Monoclonal antibodies
b. Polyclonal antibodies
c. Both a and b
d. None of these
31. Test used for AIDS is
a. Widal test
b. ELISA
c. Aggluatination
d. CFT
32. Antibody having high valency is
a. IgG
b. IgA
c. IgD
d. IgM
33. Intensity of attraction between antigen and antibody molecule is known as
a. Affiniy
b. Avidity
c. Reaction
d. None of these
34. Active immunity is induced by
a. Infection
b. Placental transfer of antibodies
c. Injection of antibodies
d. Injection of gamma- globulins
35. Pasteur developed the vaccines for
a. Anthrax
b. Rabies
c. Chicken cholera
d. All of the above
36. Delayed type of hypersensitivity is seen in
a. Penicillin allergy
b. Contact dermatitis
c. Arthus reaction
d. Anaphylaxis
37. The following are used for the preservation of virus, except
a. Freezing (–20°C–70°C)
b. Lyophilization
c. Ether
d. Formaldehyde
38. Antibody formation depends on
a. Age of the person
b. Amount of antigen
c. Wellbeing of the person
d. All of the above
39. Local immunity is important in
a. Influenza
b. Allergy
c. Polio
d. All of these
40. Role of magnesium in vaccine is
a. Adjuvant
b. Stabilizer
c. Conditioner
d. All of these
41. Immunity is lifelong following
a. Diphtheria
b. Tetanus
c. Measles
d. Yellow fever
42. To prepare vaccine for small pox, the material used by Edward Jenner is
a. Small pox material
b. Chicken pox material
c. Cow-pox material
d. Measles material
43. During recombination, strain that Donates genetic material frequently with high rate:
a. Hfr-Strain
b. F+-Strain
c. F-Strain
d. both a and c
44. The character acquired by the cell due to recombination is
a. Inheritable
b. Syppressed
c. Dominating
d. Heritable
45. T-cells are produced from
a. Bonemarrow
b. Thymus
c. Spleen
d. None of these
46. Antibodies are produced from
a. T-cells
b. â-cells
c. NK cells
d. Eosinophils
47. Incomplete antigens are called
a. Immunogens
b. Epitomes
c. Haptens
d. Paratope
48. To be antigen, the chemical molecule (protein) needs
a. High molecular weight
b. Chemical complexity
c. Both a and b
d. None of these
49. The parts which filter lymph are
a. Lymph nodes
b. Spleen
c. Thymus
d. Bone marrow
50. The primary cells involved in immune response are
a. NK-cells
b. K-cells
c. Lymphocytes
d. None of these