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PHARMACEUTICAL CHEMISTRY-ll Mcq Test Paper

PHARMACEUTICAL CHEMISTRY-ll
Mcq Test Paper

1. uses of Paracetamol
(a) In treatment of haemorrhage
(b) in palliative treatment of neoplasm of gastrointestinal tract
(c) Analgesics for relief of pain such as headache, toothache, neuralgia
(d) To treat hypoprothrombinemia.

2.uses of Proflavine
(a) used for local infection of external ear, mouth,
(b) Alone or in conjunction with radiotherapy
(c) It is effective against many gram positive and gram negative bacteria. 
(d) All of the above

3.uses of 5-fluorouracil
(a) Antipyretic.
(b) It is slow acting antiseptic.
(c) It is used in treatment of infected wounds
(d) To treat solar keratoses and other malignant conditions of skin.

4.uses of Atropine
(a) To treat parkinsonism
(b) In small doses it is CNS stimulant
(c) Due to antimuscarinic activity
(d) All of the above

5.uses of Propranolol
(a) To treat acute rhinitis, hay fever
(b) It is used to treat cardiac arrhythmia
(c) For gastric and duodenal ulcer
(d) For anaesthetic premedication

6.Importance of vitamin A
(a) It is used for treating vitamin A deficiency
(b) Vitamin A is important for growth, development and maintenance of immune system
(c) Vitamin A is also used for skin conditions including acne, eczema, psoriasis, cold sores, wounds, burns, sunburn.
(d) All of the above

7.uses of ‘Thyroxine
(a) To suppress Goitre
(b) To treat cretinism
(c) To treat thyrotoxicosis.
(d) All of the above

8.Uses of Chloramphenicol
(a) Used as mydriatic.
(b) It has antihistamine properties.
(c) It is applied locally for treatment of ear, eye and skin infection.
(d) Used in treatment of acute mania & delirium with morphine

9.Uses of Salbutamol
(a) Treatment of asthma. 
(b) It is used for relief of withdrawal symptoms of morphine dependence.
(c) Used in allergic conditions.
(d) It was used in the treatment of typhoid.

10.Uses of Hyoscine
(a) It also has tranquilizing action.
(b) Used in motion sickness.
(c) Prevention of bronchospasm
(d) It may be used as a second-line agent in the treatment of tetracycline-resistant cholera.

11.Uses of Promethazine
(a) It is also useful in the treatment of brain abscesses.
(b) It has bronchodilator action
(c) It is used in treatment of Rickettsia, Chlamydia and mycoplasma
(d) Used as an antiemetic drug. 

12.Uses of testosterone
(a) They also find use in the treatment of gynaecomastia.
(b) They also find use in the treatment of disseminated breast cancer in postmenopausal women
(c) Testosterone as well as other androgenic compounds find use in the male for replacement in hypogonadism, eunuchoidism & the male climacteric.
(d) All of the above

13.Uses of diphenhydramine
(a) It is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu
(b) It reduces the effects of natural chemical histamine in the body.
(c) Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
(d) used to prevent and treat nausea, vomiting and dizziness caused by motion sickness. 

14.Uses of Halothane
(a) It is used in cardiac arrhythmias.
(b) It is the most potent anaesthetic & is administered by inhalation.
(c) It is a thiazide diuretic that helps prevent your body from absorbing too much salt, which can cause fluid retention.
(d) It is used to help you relax and fall asleep.

15.Uses of Phenytoin
(a) It is used to treat symptoms of depression.
(b) It is used to treat fluid retention (edema) in people with congestive heart failure
(c) It is used in symptomatic therapy of epilepsy
(d) Induction of anaesthesia by halothane is smooth & rapid, & does not cause irritation to the mucous membrane.

16.Uses of Hydrochlorothiazide
(a) It is used to treat high blood pressure
(b) It is the drug of choice in preventing major convulsive seizures
(c) It is a tricyclic antidepressant.
(d) It is sometimes used to treat bed-wetting in children ages 6 and older.

17.uses of imipramine.
(a) Some of them also have “anorexia” effects.
(b) It affects chemicals in the brain that may be unbalanced in people with depression.
(c) Useful as respiratory stimulants & this action is brought about through chemo receptors & the vasomotor centre.
(d) It is used in combination with pyrimethamine in the treatment of malaria

18.uses of Coramine
(a) These drugs are used to improve wakefulness in patients that have narcolepsy
(b) It is a primary drug in the treatment of hepatic amoebiasis.
(c) It has antiprotozoal and antibacterial action
(d) It is active against anaerobic bacteria like streptococci and H-Pylori

19.uses of metronidazole.
(a) Respiratory tract infection
(b) It is used in the treatment of severe intestinal amoebiasis
(c) Gonorrhea
(d) Meningitis

20.Properties of Phenobarbitone
(a) It may exhibit polymorphism.
(b) It has a bitter taste.
(c) It is soluble in water and alcohol, slightly soluble in chloroform and solution of alkali hydroxide and carbonates.
(d) It is white, crystalline, odorless solid.

21.Properties of clofibrate.
(a) It is very slightly soluble in water; miscible with alcohol, chloroform & ether.
(b) It is a stable, clear, and colorless to pale yellow liquid with a characteristic faintly acrid odor. 
(c) It occurs as a bright yellow crystalline powder.
(d) It is practically insoluble in water, sparingly soluble in alcohol & soluble in chloroform.

22.Uses of Pilocarpine
(a) Used for reversal of post-operative over sedation
(b) Decreases intraocular pressure in glaucoma
(c) Used for the treatment of poisoning due to anticholinergic and Tricyclic antidepressants
(d) To treat some psychiatric and neurological disorders( e.g. Alzheimer’s disease)

23.Uses of Physostigmine
(a) For accommodation of near vision of eye
(b) For diagnosis of Adie’s pupil
(c) Used in solutions of 1 to 5% as miotic to constrict pupil.
(d) Used as miotic

24.Uses of Menadione
(a) Coagulants
(b) In treatment of haemorrhage.
(c) To treat hypoprothrombinemia.
(d) All of the above

Give the brand names

25.Phenformin
(a) Mejorol
(b) Sucronase
(c) Cadicyclin
(d) Anacin

26.Tetracycline
(a) Powerin
(b) Aspro
(c) Diaformin
(d) Enterocyclin

27.Aspirin
(a) Bislim
(b) Achromycin
(c) Coldarin
(d) codopyrin
(e) Both (c) & (d)

Name the drug used in

28.Myasthenia gravis
(a) thiambutosin
(b) Bromocriptine,
(c) Neostigmine
(d) cycloserine

29.Leprosy
(a) Physostigmine
(b) Dapsone
(c) selegiline
(d) Biperiden

30.Gout
(a) Bromocriptine
(b) Pyridostigmine
(c) solapsone
(d) Naproxen

31.Tuberculosis
(a) thiacetazone
(b) Celecoxib
(c) Isoniazide
(d) Amantadine

32.Parkinsonism
(a) Allopurinol
(b) clofazimine
(c) pyrazinamide
(d) Atropine

State whether the following statements are True or False

33.Vitamins may be defined as potent organic substances which are essential for normal growth and maintenance of life of human and animals, which are not able to synthesize in adequate quantity
(a) True
(b) False

34.Drugs which promote excretion of water & electrolytes from the body through kidneys in the form of urine are called diuretics.
(a) True
(b) False

35.As insulin is affected by heat & light, all insulin preparations must be stored at low temperatures between 2-8°C. It should not be allowed to freeze.
(a) True
(b) False

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