PHARMACEUTICS
51. Turbulent flow occurs when Reynolds number ReD is?
A. Re < 2100
B. Re > 2100
C. Re > 4000
D. Re Between 2300 to 4000
52. Transition flow occurs when Reynolds number ReD is?
A. Re < 2100
B. Re > 2100
C. Re > 4000
D. Re Between 2300 to 4000
53. One of the following mills works on both the principles of attrition and impact
a) Cutter mill
b) Hammer mill
c) Roller mill
d) Fluid energy mill
54. One of the following apparatus is used to determine the particle size by the gravity sedimentation method
a) Pyknometer
b) Oswald viscometer
c) Andreasen apparatus
d) Friabilator
55. One of the following equation is used to predict the stability of a drug product at room temperature from experiments at accelerated temperature
a) Stokes equation
b) Arrhenius equation
c) Yong equation
d) Micaelis-Menton equation
56. If Carr’s index of a powder is 5-15 % then the type of powder flow is
a) Poor b) Excellent
c) Very poor d) good
57. If Carr’s index of a powder is 36-40 % then the type of powder flow is
a) Poor
b) Excellent
c) Very poor
d) good
58. The ratio of the void volume to the bulk volume of the packing of the powder is called
a) Porosity
b) True density
c) Granular density
d) Bulk density
59. A sample of calcium oxide powder with a true density of 3.203 and weighing 131.3g was found to have a bulk volume of 82 cm3 when placed in a 100-ml graduated cylinder. Calculate the Porosity = ε =?
A. 50%
B. 30%
C. 40%
D. 75%
60. If Carr’s index of a powder is 50% then the type of powder flow is
a) Poor
b) Excellent
c) Very poor
d) Extremely poor
61. Hausner ratio Value less than 1.25 indicates?
A. Good flow
B. Poor flow
C. Excellent flow
D. Extremely poor flow
62. Hausner ratio value greater than 1.5 indicates?
A. Good flow
B. Poor flow
C. Excellent flow
D. Extremely poor flow
63. Unit of Hausner ratio is?
A. unitless
B. gm/cm2
C. gm/sec
D. gm/cm3
64. The rougher and more irregular the surface of the particles, the_____ will be the angle of repose?
A. Higher
B. Lower
C. No such relation
D. None of this
65. The Angle of repose less than 20 than?
a) Excellent flow
b) Good flow
c) Passable flow
d) Poor flow
66. The Angle of repose between 20-30 than?
a) Excellent flow
b) Good flow
c) Passable flow
d) Poor flow
67. The Angle of repose between 30-34 than?
a) Excellent flow
b) Good flow
c) Passable flow
d) Poor flow
68. The Angle of repose greater than 40?
a) Excellent flow
b) Good flow
c) Passable flow
d) Poor flow
69. Generally, more spherical particles have poor flow properties than more irregular particles. Statement is?
A. False
B. True
C. Depend on the material
D. can’t say anything
70. SURFACE TENSION [γ] is the force per unit length that must be applied parallel to the surface so as to counterbalance the net inward pull and has the units of
A. dyne/cm
B. dyne/cm2
C. dyne.cm
D. dyne.cm2
71. Stalagmometer use to measure?
A. viscosity B. surface tension
C. density D. None
72. FIND OUT TRUE
P. Spans with low HLB are lipophilic.
Q. Tweens with high HLB are hydrophilic.
A. Only P is true.
B. Only Q is true
C. Both P & Q True
D. Bothe P & Q False
73. FIND OUT TRUE
P. Spans with high HLB are lipophilic.
Q. Tweens with low HLB are hydrophilic.
A. Only P is true.
B. Only Q is true
C. Both P & Q True
D. Bothe P & Q False
74. The higher the HLB of a surfactant the more………..in nature.
A. Hydrophilic
B. Lipophilic
C. Amphiphilic
D. None of this
75. The relationship between pressure of the gas and amount adsorbed at constant temp has been expressed by
A. Freundlich isotherm equation
B. Langmuir isotherm equation
C. Beers’s isotherm equation
D. Lamberts isotherm equation
76. The adsorption of gas on the solid surface depends on the pressure of the gas in the experimental conditions. Statement of?
A. Freundlich isotherm equation
B. Langmuir isotherm equation
C. Beers’s isotherm equation
D. Lamberts isotherm equation
77. Which one is true about Wetting agent?
A. Wetting agent is a surfactant.
B. Lower the contact angle
C. displacing the air phase at the surface and replacing it with a liquid phase.
D. All Above
78. Water with a value of …….. Will not wet polyethylene with a critical surface tension of ………..
A. 72 dynes/cm & 31 dynes/cm.
B. 62 dynes/cm & 41 dynes/cm
C. 52 dynes/cm & 51 dynes/cm
D. 42 dynes/cm & 61 dynes/cm
79. A contact angle is _______, the solid is called wettable?
A. lower than 900
b. wider than 900
c. lower than 1800
d. wider than 1800
80. A contact angle is _______, the solid is called non-wettable
A. lower than 900
B. wider than 900
C. lower than 1800
D. wider than 1800
81. A contact angle equal to……..indicates complete wettability.
A. 0
B. 90
C. 180
D. 270
82. Anionic surfactants?
A. Sodium Lauryl Sulfate
B. Triethanolamine dodecyl sulfate
C. Sodium dialkvlsulfosuccinates
D. All of the above
83. Cationic surfactants?
A. Benzalkonium chloride
B. Cetylpyridinium chloride
C. Cetyltrimethylammonium bromide
D. All of the above
84. Ampholytic Surfactants?
A. Benzalkonium chloride
B. Cetylpyridinium chloride
C. Cetyltrimethylammonium bromide
D. Dodecyl-βalanine
85. Non-ionic surfactants?
A. Tweens,
B. Spans,
C. Brij and Myrj
D. All above
86. ZnO in mineral oil, certain pastes, paints and ointments show.
A. Plastic Flow
B. Pseudoplastic Flow
C. Dilatent Flow
D. None
87. U = F – f / G equation for?
A. Plastic Flow
B. Pseudoplastic Flow
C. Dilatent Flow
D. None
88. Pseudoplastic Flow is shown by?
A. Tragacanth in water
B. Sod. Alginate in water
C. Methyl cellulose in water
D. All above
89. Which one is true about dilatant flow?
P. It is a Shear thickening system
Q. when stress is removed, dilatant system return to its original position
A. P true Q is false
B. P false Q is true
C. P is true Q is true
D. P is false Q is false
90. Certain suspensions with high % of dispersed solids shows?
A. Plastic Flow
B. Pseudoplastic Flow
C. Dilatent Flow
D. None
91. Ostwald viscometer is which type of viscometer?
A. Single point viscometer
B. Multi point viscometer
C. Rotational viscometers
D. All above
92. Cup and Bob viscometer is which type of viscometer?
A. Single point viscometer
B. Capillary viscometer
C. Rotational viscometers
D. All above
93. Gold number for Potato starch?
A. 5
B. 10
C. 15
D. 25
94. Gold number for Gum tragacanth?
A. 2
B. 4
C. 6
D. 8
95. Zsigmondy introduced which term?
A. Gold number?
B. Reynolds number
C. Wave number
D. None of this
96. Hammer mill is mostly used for
A. Wet granulation
B. Dry granulation
C. both
D. None
97. Generally the ball mills are operated at ……. of critical speed.
A. 30-45%
B. 60-85%
C. 10-25%
D. 40-65%
98. Size reduction of Fibrous material is done by?
A. Hammer mill
B. Roller attrition
C. Fluid energy mill
D. Cutter mill
99. Colloid mill mostly used for production of
A. Emulsions
B. Solutions
C. Suspensions
D. Dry Syrup
100. Natural tendency to lose water is called?
A. Efflorescent
B. Deliquescent
C. Hygroscopic
D. None