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pharmacyTopic wise MCQs

Physical Pharmacy II MCQs with Answers

by Ronakpatel06470

1. When one of the reactants is present in such great excess then its concentration may be considered constant or nearly so, the reaction is said to be ________

  1. (a) Zero order
  2. (b) Apparent zero order
  3. (c) First order
  4. (d) Second order

2. The particle size range of colloidal dispersion is _____

  1. (a) 1 nm to 1 µm
  2. (b) 1 nm to 0.5 µm
  3. (c) 1 nm to 100 nm
  4. (d) Greater than 100 nm

3. Inorganic particles such as gold and silver dispersed in water form ___________

  1. (a) Lyophilic
  2. (b) Lyophobic
  3. (c) Amphiphilic
  4. (d) they do not form colloids

4. Suspension follows _____ kinetics.

  1. (a) Zero-order
  2. (b) Apparent zero-order
  3. (c) First order
  4. (d) Pseudo order

5. Influence of temperature on drug decomposition is expressed by

  1. (a) Arrhenius equation
  2. (b) Rutherford’s equation
  3. (c) Langmuir’s isotherm
  4. (d) BET equation

6. Permitted amount of drug degradation during its shelf life is

  1. (a) 1%
  2. (b) 10%
  3. (c) 15%
  4. (d) 90%

7. Guidelines on stability testing are given by

  1. (a) USP
  2. (b) Govt. of India
  3. (c) ICH
  4. (d) BPC

8. Accelerated stability studies help in predicting …………

  1. (a) expiry date
  2. (b) solubility
  3. (c) order
  4. (d) molecularity

9. Specific reaction rate constant is a parameter of

  1. (a) chemical reaction
  2. (b) suspension
  3. (c) Dissolution
  4. (d) Diffusion

10. Molecularity of reaction gets influenced by ………..

  1. (a) time
  2. (b) pressure
  3. (c) temperature
  4. (d) it never changes

11. Molecularity of a reaction can never be ……………..

  1. (a) 1
  2. (b) 2
  3. (c) 3
  4. (d) 0

12. Dissolution rate can be determined by ……………

  1. (a) Fick’s law
  2. (b) Arrhenius equation
  3. (c) Noyes Whitney equation
  4. (d) Henderson Hasselbalch equation

13. Transport cell is used for measurement of ………………….

  1. (a) dissolution rate
  2. (b) diffusion rate
  3. (c) order
  4. (d) molecularity

14. Molecular dispersions have size …………………

  1. (a) less than 1nm
  2. (b) equal to 1 nm
  3. (c) more than 1nm
  4. (d) more than 2 nm

15. Molecular dispersions undergo ………….

  1. (a) no diffusion
  2. (b) slow diffusion
  3. (c) rapid diffusion
  4. (d) sedimentation

16. Suspension is an example of …………

  1. (a) colloid
  2. (b) coarse dispersion
  3. (c) true solution
  4. (d) semisolid

17. Dispersed phase and dispersion medium are components of …….

  1. (a) liquids
  2. (b) dispersions
  3. (c) solids
  4. (d) semisolids

18. Glucose in water will be an example of ………….

  1. (a) suspension
  2. (b) emulsion
  3. (c) colloids
  4. (d) true solution

19. Polymer solutions are examples of …………..

  1. (a) suspension
  2. (b) emulsion
  3. (c) colloidal dispersion
  4. (d) true solution

20. Emulsions are having ……….. as one of their components.

  1. (a) Diluents
  2. (b) Glidants
  3. (c) Coating material
  4. (d) emulsifying agents

21. Emulsions are destabilized when they are ………….

  1. (a) heated
  2. (b) cooled
  3. (c) kept at room temperature
  4. (d) prepared

22. Emulsions are examples of ………….

  1. (a) colloid
  2. (b) coarse dispersion
  3. (c) true solution
  4. (d) semisolid

23. Flocculation is a phenomenon seen in …………..

  1. (a) suspensions
  2. (b) solutions
  3. (c) emulsions
  4. (d) semisolids

24. Full form of BCS is ……………..
(a) Biopharmaceutical Classification System
(b) Biological Classification System
(c) Bioinformatics Classical System
(d) Biopharmaceutics Classical System

25. Suspensions are ……………….

  1. (a) molecular dispersions
  2. (b) true solutions
  3. (c) coarse dispersions
  4. (d) colloids

26. Shelf life determination of pharmaceutical dosage form uses the principles of …………..

  1. (a) Arrhenius equation
  2. (b) Rutherford’s equation
  3. (c) Langmuir’s isotherm
  4. (d) BET equation

27. For a chemical reaction to occur there is need of proper collision of reacting molecules along with sufficient kinetic energy. It is stated by……………………..

  1. (a) Electronic theory
  2. (b) Collision theory
  3. (c) Activated complex theory
  4. (d) BCS

28. Order of a chemical reaction can be estimated from the ……..

  1. (a) molecularity
  2. (b) molecular formula
  3. (c) rate law
  4. (d) melting point

29. Emulsions are thermodynamically ………….

  1. (a) stable
  2. (b) safe
  3. (c) unstable
  4. (d) unsafe

30. Effect of temperature on rate of a chemical reaction is explained by ………..

  1. (a) (a) Electronic theory
  2. (b) Collision theory
  3. (c) Activated complex theory
  4. (d) Arrhenius equation

31. In flocculation occurring in suspension, the particles in floccules are held by ______?

  1. (a) Repulsive forces
  2. (b) Gravitational force
  3. (c) Vanderwaal forces
  4. (d) None of the above

32. Which of the following is an instability of emulsion?

  1. (a) Breaking
  2. (b) mottling
  3. (c) uneven surface
  4. (d) picking

33. Coalescence is a phenomenon that is observed in …………….

  1. (a) Suspensions
  2. (b) emulsions
  3. (c) suppositories
  4. (d) tablets

34. Surfactants play the role of ………………

  1. (a) increasing viscosity
  2. (b) reducing surface tension
  3. (c) increasing kinetic energy
  4. (d) increasing sedimentation

35. The purpose of an emulsifier is to ………

  1. (a) decrease surface area in suspension
  2. (b) reduces interfacial tension between immisciblephases
  3. (c) minimizes globule size
  4. (d) improves taste of medication

36. Ethylene diamine tetraacetic acid (EDTA) is a ………………………..type of ligand.

  1. (a) Unidentate
  2. (b) bidentate
  3. (c) tetradentate
  4. (d) hexadentate

37. Ligands with multiple binding sites are called ………

  1. (a) Unidentate
  2. (b) bidentate
  3. (c) tetradentate
  4. (d) polydentate

38. The ______ sphere is enclosed in brackets in formulas for complex species, and it includes the central metal ion plus the coordinated groups.

  1. (a) ligand
  2. (b) donor
  3. (c) oxidation
  4. (d) coordination

39. In coordination chemistry, the donor atom of a ligand is ……………

  1. (a) a Lewis acid
  2. (b) the counter ion
  3. (c) the central metal atom.
  4. (d) the atom in the ligand that shares an electron pair with the metal.

40. What is the driving force for Fick’s law?

  1. (a) Concentration
  2. (b) concentration gradient
  3. (c) pressure
  4. (d) temperature

41. Particles settle down under the influence of gravity in ………………..

  1. (a) True solutions
  2. (b) Colloids
  3. (c) Suspensions
  4. (d) Molecular dispersions

42. Lyophobic colloids are also called as ……………………

  1. (a) Solvent loving
  2. (b) solvent hating
  3. (c) solvent neutral
  4. (d) solvent non reacting

43. Lyophilic colloids are also known as ……………………..

  1. (a) Solvent loving
  2. (b) solvent hating
  3. (c) solvent neutral
  4. (d) solvent non reacting

44. Sand in water is an example of …………………

  1. (a) Solution
  2. (b) suspension
  3. (c) emulsion
  4. (d) colloid

45. Sugar in water is an example of ………………..

  1. (a) Solution
  2. (b) suspension
  3. (c) emulsion
  4. (d) colloid

46. Tyndal effect is exhibited by …………………..

  1. (a)Solution
  2. (b) suspension
  3. (c) emulsion
  4. (d) colloid

47. Brownian movement is exhibited by …………………..

  1. (a)Solution
  2. (b) suspension
  3. (c) emulsion
  4. (d) colloid

48. Phase inversion is exhibited by ………………………..

  1. (a)Emulsions
  2. (b) suspension
  3. (c) solution
  4. (d) colloid

49. Dissolution rate studies are carried out by …………….. apparatus.

  1. (a)Homogenizer
  2. (b) stability chamber
  3. (c) dissolution testing apparatus
  4. (d) Horizontal transport cell

50. The reaction where the rate is independent of concentration of reactants is called as …………order reaction.

  1. (a) Zero
  2. (b) first
  3. (c) pseudo
  4. (d) second
Physical Pharmacy II
Answer Key

Q1).b
Q2).b
Q3).b
Q4).b
Q5).a
Q6).b
Q7).c
Q8).a
Q9).a
Q10).d
Q11).d
Q12).c
Q13).b
Q14).a
Q15).c
Q16).b
Q17).b
Q18).d
Q19).c
Q20).d
Q21).a
Q22).b
Q23).a
Q24).a

Q25.c
Q26.a
Q27.b
Q28.c
Q29.c
Q30.d
Q31.c
Q32.a
Q33.b
Q34.b
Q35.b
Q36.d
Q37.d
Q38.d
Q39.d
Q40.b
Q41.c
Q42.b
Q43.a
Q44.b
Q45.a
Q46.d
Q47.d
Q48.a
Q49.c
Q50.a