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pharmacy Topic wise MCQs

PRE-GPAT Preparation MCQs (Part:- 12) with Answers

PRE-GPAT MOCK TEST

Q.1 If Aloe barbadensis (Curacao) is mounted in cresol and viewed under polarized light, crystalline aloe, insoluble in cresol shows

  1. a) Dull dark color
  2. b) no color
  3. c) shining bright color
  4. d) none of these

Q.2 Diaryl Isoxazole heterocyclic ring system is present in which of these COX2 Inhibitors?

  1. a) Valdecoxib
  2. b) Rofecoxib
  3. c) Celecoxib
  4. d) Etoricoxib

Q.3 This reaction is known as

  1. a) Willgrode-Kindler
  2. b) Ullman reaction
  3. c) Michael addition
  4. d) Kolbe reaction

Q.4 Benzaldehyde and cyanoacetic acid ester are used to prepare

  1. a) Trimethadone
  2. b) Phenytoin
  3. c) Carbamezapine
  4. d) Phensuximide

Q.5 A eye drop should comply the following test except

  1. a) Sterility
  2. b) Pyrogen
  3. c) Content of drug
  4. d) Isotonicity

Q.6 Moisture content of aerosol product is determined by

  1. a) Karl-Fisher method
  2. b) UV-spectroscopy
  3. c) Toluene distillation
  4. d) IR-spectroscopy

Q.7 The content uniformity test for tablets as per I.P. is used to ensure which quality?

  1. a) Purity
  2. b) Bioequivalence
  3. c) Weight variation
  4. d) Potency

Q.8 Minimum expiry date for a tablet should be

  1. a) 5 years
  2. b) 3 years
  3. c) 2 years
  4. d) 10 years

Q.9 Disintegration test is not applicable for

  1. a) Sugar coated tablet
  2. b) Film coated tablet
  3. c) Sustain release tablet
  4. d) Soft capsule

Q.10 Radiation are used for the terminal sterilization of

  1. a) Solution
  2. b) Ointment
  3. c) Suspension
  4. d) Elixir

Q.11 The nuclei does not exhibit the NMR phenomenon, if

  1. a) Mass no. is odd & Atomic no. is odd
  2. b) Mass no. is odd & Atomic no. is even
  3. c) Mass no. is even & Atomic no. is even
  4. d) Mass no. is even & Atomic no. is odd

Q.12 (-) – Hyoscyamine is
a) 15-20 times more active as a mydriatic than (+) – hyoscyamine
b) Inactive as mydratic action
c) 3-5 times less active as a mydriatic than (+) – hyoscyamine
d) 100 times more active as a mydriatic than (+) – hyoscyamine

Q.13 When ammonium chloride is gradually and slowly incorporated into an emulsion Stabilized with ammonium oleate,

  1. a) Emulsion will crack immediately
  2. b) it will invert from w/o to o/w type
  3. c) It will invert from o/w to w/o type
  4. d) there will be no impact on its physical stability

Q.14 Sumatriptan used in acute migraine is a

  1. a) 5HT1D receptor agonist
  2. b) 5HT1D receptor antagonist
  3. c) 5HT3 receptor agonist
  4. d) 5HT3 receptor antagonist

Q.15 In Protein biosynthesis adaptor molecule is

  1. a) mRNA
  2. b) tRNA
  3. c) hnRNA
  4. d) cDNA

Q.16 Quinoline and quinclidine heterocyclic rings are found in alkaloid

  1. a) Morphine
  2. b) Chloroquine
  3. c) Mefoquine
  4. d) Cinchonidine

Q.17 When alkaloidal drug is treated with picric acid produces yellow color in

  1. a) Meyer test
  2. b) Hager test
  3. c) Wegner test
  4. d) Dragendorff test

Q.18 What is the pH of lachrymal fluid?

  • a) 5 – 5.5
  • b) 6 – 6.5
  • c) 7.2 – 7.4
  • d) 3 – 3.5

Q.19 Typhus vaccine IP is sterile suspension of

  1. a) The killed rickettsiae organisms of a strain
  2. b) one or more strains of Salmonella typhi
  3. c) One or more strains of Salmonella paratyphi
  4. d) none of these

Q.20 Hydrochlorthiazide IP is assayed by

  1. a) Perchloric acid
  2. b) Spectrophotometry
  3. c) HPLC
  4. d) Tetra butyl ammonium hydroxide

Q.21 An unsaturated ketone has absorption band with λmax at 215 nm and ε 10,000. A solution of this ketone showed absorbance A = 2.0 with 1 cm cell. Calculate the concentration of ketone in this solution

  1. a) 1 × 10-3 mol/lit.
  2. b) 2 × 10-4 mol/lit
  3. c) 1 × 10-4 mol/lit
  4. d) 2 × 10-3 mol/lit

Q.22 Weight (lb)/150 × Adult’s dose is formula for calculating child dose and known as

  1. a) Young’s formula
  2. b) Fries’s formula
  3. c) Clark’s formula
  4. d) none

Q.23 Deficiency of enzyme glucocereberosidase is known as

  1. a) Krabbe’s disease
  2. b) Gaucher’s disease
  3. c) Nickman’s disease
  4. d) Tay sach syndrome

Q.24 Which of the following occurs in cell cytoplasm?
a) Citric acid cycle
b) Urea cycle
c) Embeden Mayer of pathway
d) Oxidative phosphorylation

Q.25 Which type of stomata is present on coca leaves?

  1. a) Paracytic
  2. b) Dicytic
  3. c) Anomocytic
  4. d) Anisocytic

Q.26 Which herb is most frequently used to treat anxiety?

  1. a) Kava
  2. b) Hawthorn
  3. c) Feverfew
  4. d) Ginseng

Q.27 Which of the following is not used in IR sample preparation?

  1. a) Sodium chloride
  2. b) Ferric chloride
  3. c) Potassium bromide
  4. d) Cesium fluoride

Q.28 Bordetella bronchiseptica test organism is used for microbiological assay of

  1. a) Bacitracin
  2. b) Bleomycin
  3. c) Streptomycin
  4. d) Polymixin B

Q.29 Standard for umbilical tapes comes under ……according to Drugs & Cosmetic Act

  1. a) Schedule FIII
  2. b) Schedule F1
  3. c) Schedule FII
  4. d) Schedule FF

Q.30 Requirement of factory premises, plant, equipment etc. for manufacture of cosmetics comes under ……according to Drugs & Cosmetic Act.

  1. a) Schedule MIII
  2. b) Schedule M1
  3. c) Schedule MII
  4. d) Schedule M

Q.31 HLB value for solubilizing agents is

  1. a) 1 – 3
  2. b) 4 – 6
  3. c) 7 – 9
  4. d) 16 – 18

Q.32 Pharmacy Council of India was constituted in ……year.

  1. a) 1947
  2. b) 1948
  3. c) 1949
  4. d) 1950

Q.33 The pKa of the mepivacaine is 8.7. If the pH of the infected tissue is 9.7, the fraction of the drug in the ionized form will be

  1. a) 1 %
  2. b) 10 %
  3. c) 90 %
  4. d) 99 %

Q.34 Castor oil shows which type of flow?

  1. a) Plastic flow
  2. b) Pseodoplastic flow
  3. c) Dilatant flow
  4. d) Newtonian flow

Q.35 What is chemical name of caffeine?

  1. a) 1, 3 dimethyl xanthine
  2. b) 1, 3, 7-trimethyl xanthine
  3. c) 3, 7-dimethyl xanthine
  4. d) none

Q.36 Sarasaspogenin is used to prepare

  1. a) Cortisone
  2. b) Progesterone
  3. c) Testosterone
  4. d) Vitamin A

Q.37 2-hydroxy methylene-17β hydroxyl-17-methyl-5α-androstan-3-one is IUPAC name of which of the anabolic steroid

  1. a) Stanazole
  2. b) Oxymetholone
  3. c) Oxandrolone
  4. d) Fluxymestrone

Q.38 A seed having action on heart, What is the name of the drug?

  1. a) Digitoxin
  2. b) Digoxin
  3. c) Gitoxin
  4. d) Auabain

Q.39 In what proportion 80 % and 30 % alcohol be mixed to obtain 50 % alcohol?

  1. a) 20 parts of 80 % & 30 parts of 30 %
  2. b) 30 parts of 80 % & 20 parts of 30 %
  3. c) 40 parts of 80 % & 10 parts of 30 %
  4. d) 25 parts of 80 % & 25 parts of 30 %

Q.40 Darcy equation is used to study

  1. a) Evaporation rate
  2. b) Filtration rate
  3. c) Sedimentation rate
  4. d) Flow rate

Q.41 Reserpine on treatment with solution of vanillin in acetic acid shows

  1. a) Blue color
  2. b) Pink color
  3. c) Yellow color
  4. d) Voilet color

Q.42 Which of the following is a true alkaloid?

  1. a) Aconite
  2. b) Caffeine
  3. c) Atropine
  4. d) Conessine

Q.43 Suitable masking flavor for salty liquid oral formulation is

  1. a) Butterscotch
  2. b) Chocolate
  3. c) Mint
  4. d) Citrus fruit

Q.44 One of the following drugs does not produced nephrotoxicity?

  1. a) Amphotericin B
  2. b) Cisplatin
  3. c) Cyclosporin
  4. d) none of these

Q.45 Bubble point test is used to determine
a) Viscosity of liquid
b) Particle size
c) Surface tension of liquid in capillary tube
d) Particle volume by Anderson pippate

Q.46 Xerogel is formed

  1. a) After addition of large amount of liquid
  2. b) after removing the liquid
  3. c) Addition of large amount of solid
  4. d) none of these

Q.47 If internal stresses in the film exceed tensile strength of the film, what phenomenon will occur?

  1. a) Hazing
  2. c) Picking
  3. c) Cracking
  4. d) Blooming

Q.48 Which of the following instrument is used for tablet coating?

  1. a) Zanasi
  2. b) Chilsonator
  3. c) Ultrasonifier
  4. d) Accela cota

Q.49 Rutin or quercetin is obtained from Fagospyrum esculentum (Ruta graveleons) is also known as

  1. a) Vitamin P
  2. b) Vitamin B12
  3. c) Vitamin K
  4. d) Vitamin A

Q.50 Verbascum Thapsus shows presence of…………trichomes.

  1. a) Lignified
  2. b) Candelabra
  3. c) Warty
  4. d) none of these

Answers

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