1. Molluscum contagiosum is caused by:
- A. Papilloma virus
- B. Herpes virus
- C. Pox virus
- D. EB virus
2. Xeroderma pigmentosum is characterised by the following features except:
A. Autosomal recessive inheritance
B. Inability to repair sunlight-induced damage to DNA
C. Proneness to develop various skin cancers
D. Irregular accumulation of melanin in the basal layer
3. The etiologic agent implicated in epidermodysplasia verruci-formis is:
- A. Herpes virus (HSV)
- B. Pox virus
- C. EB virus
- D. Papilloma virus (HPV)
4. Herpesviruses cause the following exanthemata except:
- A. Herpes simplex
- B. Herpes zoster
- C. Vaccinia
- D. Varicella
5. The following bullous dermatosis is associated with coeliac disease:
- A. Pemphigus vulgaris
- B. Pemphigoid
- C. Erythema multiforme
- D. Dermatitis herpetiformis
6. Psoriasis has the following features except:
A. Acanthosis with thickened lower portion
B. Suprapapillary thinning of epidermis
C. Prominent granular cell layer
D. Munro abscesses in parakeratotic layer
7. Lichen planus is characterised by the following features except:
A. Marked hyperkeratosis
B. Acanthosis with elongated saw-toothed lower border
C. Band-like dermal infiltrate of inflammatory cells
D. Intact basal cell layer
8. The following conditions are premalignant except:
- A. Solar keratosis
- B. Seborrheic keratosis
- C. Bowen’s disease
- D. Xeroderma pigmentosum
9. The following tumour is commonly non-metastasising:
- A. Squamous cells carcinoma
- B. Basal cell carcinoma
- C. Melanoma
- D. Sweat gland carcinoma
10. Papillary hidradenoma occurs most commonly in the following region:
- A. Scalp
- B. Back
- C. Anogenital region
- D. Extremities
11. The following type of naevi most often progress to malignant melanoma:
- A. Compound naevus
- B. Blue naevus
- C. Dysplastic naevus
- D. Epithelioid naevus
12. The following type of malignant melanoma has worse prognosis:
A. Nodular melanoma
B. Superficial spreading melanoma
C. Acral lentiginous melanoma
D. Lentigo maligna melanoma
13. Darier-Pautrier’s abscess is composed of the following cells:
- A. Neutrophils
- B. Macrophages
- C. Plasma cells
- D. Atypical lymphoid cells
14. The following HPV types are implicated in the etiology of verruca vulgaris:
- A. Types 1, 2
- B. Types 6, 11
- C. Types 2, 3
- D. Types 16, 18
15. High risk factor for malignant melanoma include the following except:
A. Change in appearance
B. Higher age of the patient
C. More than 50 or more moles 2 mm or more in diameter
D. Uniform pigmentation
16. All are types of calcification in the skin except:
A. Metastatic calcinosis cutis
B. Dystrophic calcinosis cutis
C. Secondary calcinosis cutis
D. Subepidermal calcified nodule
17. Metatypical carcinoma is:
- A. Basosquamous carcinoma
- B. Rodent ulcer
- C. Sebaceous carcinoma
- D. Sweat gland carcinoma
18. Familial cases of malignant melanoma show germ line mutations in:
- A. p53
- B. Rb
- C. CDKN2A
- D. C-myc
19. All are immunohistochemical stains for melanoma except:
- A. HMB-45
- B. S-100
- C. Melan-A
- D. SMA
20. Which of the following is true about the behaviour of dermato- fibrosarcoma protuberans?
A. Rare metastasis, rare recurrence
B. Rare metastasis, locally recurrent
C. Frequent metastasis and recurrence
D. No metastasis or recurrence
Answer key
1) = C, 2) = D, 3) = D, 4) = C, 5) = D, 6) = C, 7) = D, 8) = B, 9) = B, 10) = C, 11) = C, 12) = A, 13) = D, 14) = A, 15) = D, 16) = C, 17) = A, 18) = C, 19) = D, 20) = B