PRE-GPAT MOCK TEST
1. In the mixing of Thymol and menthol the following type of incompatibility occurs
(A) Chemical incompatibility
(B) Therapeutic incompatibility
(C) Physical incompatibility
(D) Tolerance incompatibility
2. A positive Benedict’s test is not given by
(A) Sucrose
(B) Lactose
(C) Maltose
(D) Glucose
3. Which drug is popularly known as Hit and Run Drug?
a.Digitalis
b.Reserpine
c.Amrinone
d.Hydralazine
4. The applicability of Noyes-Whitney equation is to describe
(A) First order kinetics
(B) Zero order kinetics
(C) Mixed order kinetics
(D)Dissolution rate
5. Cancer causing gene is
A) Proto-oncogene
B) Oncogene
C) Mutable gene
D) Transposon
6. In the TCA cycle, at which of the following enzyme-catalyzed steps, incorporation of elements of water into an intermediate of the cycle takes place :
(A) Citrate synthase
(B) Aconitase
(C) Maleate dehydrogenase
(D) Succinyl Co-A synthase
7. Osazones are not formed with the
(A) Glucose
(B) Fructose
(C) Sucrose
(D) Lactose
8. Drove’s test used for
(A)Suspending agent
(C) Surfactant
(B) Wetting agent
(D) Disintegrant
9. Which is not a second messenger?
A. Amp
b. Guanylcyclase
c. Dag
d. Ip3
10. In human being XX – genotype is
A) always female
B) can be male or female
C) always male
D) commonly female with 5 per lakh being male
11. Circular stomata is seen in
a. Gloriosa
b. Colchicine
c. Digitalis
d. Buchu
12. A carbohydrate, known commonly as invert sugar, is
(A) Fructose
(B) Sucrose
(C) Glucose
(D) Lactose
13. A positive Seliwanoff’s test is obtained with
(A) Glucose
(B) Fructose
(C) Lactose
(D) Maltose
14. which is following is not a reversible phenomenon?
a.glass transition
b.melting
c.crystallization
d.none
15. A carbohydrate, commonly known asdextrose is
(A) Dextrin
(B) D-Fructose
(C) D-Glucose
(D) Glycogen
16. Treatment with alloxan destroys
A) STH cells
B) ß – cells of islets of langerhans
C) Cells of sertoli
D) Cells of leydig
17. Which one of the followingis used in therapy ofToxoplasmosis?
a. Artensunate
b. Thiacetazone
c. Ciprofloxacin
d. Pyrimethamine
18. Chloroguanide is
a) A prodrug
b) metabolited to cycloguanil
c) Biguanide
d) all of these
19. Following is used in Hodgkin’sdisease
A)Mephalan
B)Peclitaxol
C)Estramustine
D)Mechlormethamine
20. Hetrocycle present in pilocarpine is
a) Imidazole
b) Pyrimidine
c) Indole
d) Purine
21. In recent years DNA sequences mt-DNA & Y-chromosome were considered for study of human evolution because
A) Their structure is know in greater detail
B) They are unipaternal& don’t undergo recombination
C) They are small & easy to study
D) They can be studied from samples of fossil remains
22. DNA is associated with basic protein
A) Albumin
B) Actin
C) Histone
D) Globulin
23. Which Antibiotic show D-Threo isomer
a) Tetracycline
b) Aminoglycoside
c)Chloramphenicol
d)BetaLactum
24. Resting Cell Potential is
A)30-80 mV
C)0 to -10 mV
B) -30 to -80 mV
D)10-100 Mv
25. A small baby have pneumonia & fever so to avoid toxicity which NSAID is nt given.
A PCM
B CELECOXIB
C ETOROLEC
D ASPIRIN
26. What does lack refer to in lac operon
A) Lac insect
B) 1,00,000
C) Lactase
D) Lactose
27. Temoxifen is
A. Only estrogen antagonist
B. Estrogen antagonist to breastand agonist to Uterus and bone
C. Estrogen agonist to breastand antagonist to Uterus andbone
D. Only estrogen agonist
28. Following ergot alkaloids is employed in T/T of Migraine.
a) Ergometrine
b) Ergotamine
c) Ergocristine
d) Ergocryptine
29. Reserpine hydrolysis yields
a) Methyl reserpate, trimethoxy benzoic acid
b) Methyl reserpate, trimethyl benzoic acid
b) Methyl reserpate, trimethxycinnamic acid
c) Methyl reserpate, trimethylcinnamic acid
30. One of the following is water-soluble ergot alkaloid
a) Ergometrine
b) Ergotamine
c) Ergocristine
d) Ergocryptine
31. Truxilline acid on hydrolysis yields
a) Ecogonine +Methanol + Benzoic acid
b) Ecogonine + Methanol + Cinnamic acid
c) Ecogonine + Methanol + -Truxillic acid
d) Ecogonine + Methanol + Tropic acid
32. Which of the following cephalosporin has disulfiram like effect? (N)
(a) cefixime (b) cefaperazone
(c) cefuroxime (d) cefamandole
33. Colchicines is derived from
a) Lysine
b) Phenyl alanine
c) Dihydroxyphenylamine
d) Pyrosine
34. Paparerine is derived from,
a) Lysine
b) Ornithine
c) Tyrosine
d) Phenylalanine
35. Which of the following is not lysinederived alkaloid
a) Anabessine
b) Lapinine
c) Anaferine
d) Colchicine
36. One of the following is an example of pseudo-alkaloids
a) Atropine
b) Anabessine
c) Ephedrine
d) Emetine
37. Tropic acid portion in atropine is derived from
a) Proline
b) Ornithine
c) Phenyl alanine
d) Lysine
38. Cocaine on hydrolysis yields
a) Ecogonine +Methanol + Benzoic acid
b) Ecogonine + Methanol + Cinnamic acid
c) Ecogonine + Methanol + -Truxillic acid
d) Ecogonine + Methanol + Tropic acid
39. Raowolfia serpentina is distinguished from other species of Raowolfia by following microscopic character.
a) Sclerenchyma is absent
b) Narrow phloeum & consists of pavencyals with scattered sieve tissue
c) Parenchymatones secondary cortex &contain starch
d) All the above
40. Ephedrine is derived from
a) Lysine
b) Ornithine
c) Tyrosine
d) Phenylalanine
41. One of the following is not indole alkaloid
a) Ergotamine
b) Strychnine
c) Yohimbine
d) Piperine
42. Oculogyric crisis is known to be produced by all of the following drugs except
a. Trifluoperazine
b. Atropine
c. Perchlorperazine
d. Perphenazine
43. The best medium for production of penicillin is
a. Nutrient Agar
b. Corn steep liquor
c. Sulfite waste liquor
d. Whey
44. st.anton’s fire is associated with…?
a)reserpine
b)clonidine
c)ergot
d)yohimbine
45. the bacterial spores are destroyed by
a)Dessicstion
b)Phenol
c)Boilling
d)Autoclaving
46. the immunoglobin which crosses placenta is
a) 1gA
b)1gD
c)1gG
d)1Gm
47. which of the following is not a methyl xanthines derivative
a. theobromine
b. theophihylline
c. cocaine
d. caffine
48. Tailling effect in column chromatography reduce by _________elution technique.
A.Isocratic elution
B.Fractional elution
C.Gradient elution
D.None of the above
49. Dry mouth during antidepressant therapy is caused by blockade of
a. Muscarinic acetylcholinereceptors
b. Serotonergic receptors
c. Dopaminergic receptors
d. GABA receptors
50. Which one of the following drugs increases gastrointestinal motility?
a. Glycopyrrolate
b. Atropine
c. Neostigmine
d. Fentanyl
Answers
