Anti-Gout and Antirheumatic Drugs important Question For One Mark
True or False
1) Probenecid is a uricosuric drug that decreases uric acid excretion in the urine.
2) Allopurinol is a purine compound which is chemically similar to hypoxanthine.
3) Leflunomide suppresses the arthritic symptoms and also retards the radiological
progression of disease.
4) The structure of sulfasalazine consists of sulfapyridine and 6 -aminosalicylic acid.
5) Auranofin is a recombinant IL -R-receptor antagonist which the patients take daily
by their own via subcutaneous route.
Fill in the Blanks
6) Anti-gout drugs are used to treat gout and certain types of ______________.
7) Colchicine is an alkaloid obtained from _______________.
8) Allopurinol is a purine compound which is chemically similar to _______________.
9) _____________ is a potent pyrazolidine derivative, and a uricosuric agent for gout.
10) ______________ is basically an antimalarial drug, which can also be used in the treatment of RA.
11) ____________ and _________________ are the two commonly used gold salts.
Answers
1) False 2) True 3) True 4) False 5) False 6) Kidney stones 7) Colchicum autumnale 8) hypoxanthine 9) Sulfinpyrazone 10) Chloroquine 11) Sodium aurothiomalate, Auranofin
Important Summary For one mark Question
1) Gout is a hereditary me tabolic disease characterised by overproduction of uric acid.
2) Anti-gout drugs are used to treat gout and certain types of kidney stones.
3) Probenecid is a uricosuric drug that increases uric acid excretion in the urine. It is primarily used for treating gout and hyperuricemia.
4) Colchicine is an alkaloid obtained from Colchicum autumnale, and used in neoplastic disease because of its antimitotic activity.
5) NSAIDs suppress the pain and inflammation of acute gout.
6) Allopurinol is a purine compound which is chemically similar to hypoxanthin e.
7) Sulfinpyrazone is a potent pyrazolidine derivative, and a uricosuric agent for gout.
8) Rheumatoid Arthritis (RA) is a type of autoimmune disease, characterised
by the inflammation in joints, synovial proliferation, and destruction of articular cartilage.
9) Methotrexate is an i nhibitor of dihydrofolate reductase, and has immunosuppressant and anti-inflammatory action.
10) The structure of sulfasalazine consists of sulfapyridine and 5 -aminosalicylic acid.
11) Chloroquine is basically an antimalarial drug, which can also be used in the treatment of RA.
12) Leflunomide suppresses the arthritic symptoms and also retards the radiological progression of disease.
13) Sodium aurothiomalate and auranofin are the two commonly used gold salts .
14) Anakinra is a recombinant IL -R-receptor antagonist which the p atients take daily by their own via subcutaneous route.
