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Antineoplastic Drugs MCQs With Answers

Antineoplastic Drugs MCQs

1. Which factor increases the efficacy of antineoplastic drugs?
a. Drug-provoked mutations.
b. Additional immunotherapy.
c. Decrease in tumor blood supply.
d. Tumor cells acquire natural insensitivities.

2. Which antineoplastic alkylating drug is effective in treating tumors within the central nervous system (CNS)?
a. Thiotepa.
b. Busulfan.
c. Dacarbazine.
d. Temozolomide.

3. Which effect of alkylating antineoplastic agents results in greater susceptibility to infection?
a. Hepatotoxicity.
b. Myelosuppression.
c. Nausea and vomiting.
d. Nonspecific cell destruction.

4. Which antineoplastic agent is a folic acid analogue?
a. Methotrexate.
b. Mercaptopurine.
c. Cytarabine.
d. Fluorouracil.

5. Which antibiotic antineoplastic agent is used in combination with many chemotherapy protocols due to its low-toxicity profile?
a. Mitomycin.
b. Bleomycin.
c. Doxorubicin.
d. Daunorubicin.

6. Which antiestrogen drug is used to treat estrogen-dependent adenocarcinoma of the breast?
a. Megestrol.
b. Tamoxifen.
c. Prednisone.
d. Testosterone.

7. Thalidomide, an antineoplastic drug, requires the administration of which other class of drug?
a. Antibiotic.
b. Hypertension.
c. Anticoagulant.
d. Corticosteroid.

8. Which biologic response modifier affects epithelial cells to reduce mucositis?
a. Palifermin.
b. Interferon.
c. Aldesleukin.
d. Sargramostim.

9. Which is most specific and is the first-line drug used to treat patients with myeloid leukemia?
a. Imatinib.
b. Busulfan.
c. Clofarabine.
d. Methotrexate.

10. Which monoclonal antibody (MAb) is specific for HER-2/Neu (of the EGFR family), an overexpressed antigen in relation to aggressive tumors?
a. Rituximab.
b. Trastuzumab.
c. Bevacizumab.
d. Alemtuzumab.

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