BIOCHEMISTRY
1. A drug which prevents uric acid synthesis by inhibiting the enzyme xanthine oxidase is
(A) Aspirin
(B) Allopurinol
(C) Colchicine
(D) Probenecid
2. Which of the following is required for crystallization and storage of the hormone insulin?
(A) Mn++
(B) Mg++
(C) Ca++
(D) Zn++
3. Oxidation of which substance in the body yields the most calories
(A) Glucose
(B) Glycogen
(C) Protein
(D) Lipids
4. Milk is deficient in which vitamins?
(A) Vitamin C
(B) Vitamin A
(C) Vitamin B2
(D) Vitamin K
5. Milk is deficient of which mineral?
(A) Phosphorus
(B) Sodium
(C) Iron
(D) Potassium
6. Synthesis of prostaglandins is inhibited by
(A) Aspirin
(B) Arsenic
(C) Fluoride
(D) Cyanide
7. HDL is synthesized and secreted from
(A) Pancreas
(B) Liver
(C) Kidney
(D) Muscle
8. Which are the cholesterol esters that enter cells through the receptor-mediated endocytosis of lipoproteins hydrolyzed?
(A) Endoplasmin reticulum
(B) Lysosomes
(C) Plasma membrane receptor
(D) Mitochondria
9. Which of the following phospholipids is localized to a greater extent in the outer leaflet of the membrane lipid bilayer?
(A) Choline phosphoglycerides
(B) Ethanolamine phosphoglycerides
(C) Inositol phosphoglycerides
(D) Serine phosphoglycerides
10. All the following processes occur rapidly in the membrane lipid bilayer except
(A) Flexing of fatty acyl chains
(B) Lateral diffusion of phospholipids
(C) Transbilayer diffusion of phopholipids
(D) Rotation of phospholipids around their long axes
11. Which of the following statement is correct about membrane cholesterol?
(A) The hydroxyl group is located near the centre of the lipid layer
(B) Most of the cholesterol is in the form of a cholesterol ester
(C) The steroid nucleus form forms a rigid, planar Structure
D) The hydrocarbon chain of cholesterol projects into the extracellular fluid
12. Which one is the heaviest particulate component of the cell?
(A) Nucleus
(B) Mitochondria
(C) Cytoplasm
(D) Golgi apparatus
13. Which one is the largest particulate of the cytoplasm?
(A) Lysosomes
(B) Mitochondria
(C) Golgi apparatus
(D) Entoplasmic reticulum
14. The degradative Processess are categorized under the heading of
(A) Anabolism
(B) Catabolism
(C) Metabolism
(D) None of the above
15. The exchange of material takes place
(A) Only by diffusion
(B) Only by active transport
(C) Only by pinocytosis
(D) All of these
16. The average pH of Urine is
(A) 7.0
(B) 6.0
(C) 8.0
(D) 0.0
17. The pH of blood is 7.4 when the ratio between H2CO3 and NaHCO3 is
(A) 1: 10
(B) 1: 20
(C) 1: 25
(D) 1: 30
18. The phenomenon of osmosis is opposite to that of
(A) Diffusion
(B) Effusion
(C) Affusion
(D) Coagulation
19. The surface tension in intestinal lumen between fat droplets and aqueous medium is decreased by
(A) Bile Salts
(B) Bile acids
(C) Conc. H2SO4
(D) Acetic acid
20. Which of the following is located in the mitochondria?
(A) Cytochrome oxidase
(B) Succinate dehydrogenase
(C) Dihydrolipoyl dehydrogenase
(C) All of these
21. The most active site of protein synthesis is the
(A) Nucleus
(B) Ribosome
(C) Mitochondrion
(D) Cell sap
22. The fatty acids can be transported into and out of mitochondria through
(A) Active transport
(B) Facilitated transfer
(C) Non-facilitated transfer
(D) None of these
23. Mitochondrial DNA is
(A) Circular double stranded
(B) Circular single stranded
(C) Linear double helix
(D) None of these
24. The absorption of intact protein from the gut in the foetal and newborn animals takes place by
(A) Pinocytosis
(B) Passive diffusion
(C) Simple diffusion
(D) Active transport
25. The cellular organelles called “suicide bags” are
(A) Lysosomes
(B) Ribosomes
(C) Nucleolus
(D) Golgi’s bodies
26. The general formula of monosaccharides is
(A) CnH2nOn
(B) C2nH2On
(C) CnH2O2n
(D) CnH2nO2n
27. The general formula of polysaccharides is
(A) (C6H10O5)n
(B) (C6H12O5)n
(C) (C6H10O6)n
(D) (C6H10O6)n
28. The aldose sugar is
(A) Glycerose
(B) Ribulose
(C) Erythrulose
(D) Dihydoxyacetone
29. A triose sugar is
(A) Glycerose
(B) Ribose
(C) Erythrose
(D) Fructose
30. A pentose sugar is
(A) Dihydroxyacetone
(B) Ribulose
(C) Erythrose
(D) Glucose
31. The pentose sugar present mainly in the heart muscle is
(A) Lyxose
(B) Ribose
(C) Arabinose
(D) Xylose
32. Polysaccharides are
(A) Polymers
(B) Acids
(C) Proteins
(D) Oils
33. The number of isomers of glucose is
(A) 2
(B) 4
(C) 8
(D) 16
34. Two sugars which differ from one another only in configuration around a single carbon atom are termed
(A) Epimers
(B) Anomers
(C) Optical isomers
(D) Stereoisomers
35. Isomers differing as a result of variations in configuration of the —OH and —H on carbon atoms 2, 3 and 4 of glucose are known as
(A) Epimers
(B) Anomers
(C) Optical isomers
(D) Steroisomers
36. The most important epimer of glucose is
(A) Galactose
(B) Fructose
(C) Arabinose
(D) Xylose
37. ααα-D-glucose and β-D-glucose are
(A) Stereoisomers
(B) Epimers
(C) Anomers
(D) Keto-aldo pairs
38. ααα-D-glucose + 1120 → + 52.50 ← + 190 βββ-D-glucose for glucose above represents
(A) Optical isomerism
(B) Mutarotation
(C) Epimerisation
(D) D and L isomerism
39. Compounds having the same structural formula but differing in spatial configuration are known as
(A) Stereoisomers
(B) Anomers
(C) Optical isomers
(D) Epimers
40. In glucose the orientation of the —H and —OH groups around the carbon atom 5 adjacent to the terminal primary alcohol carbon determines
(A) D or L series
(B) Dextro or levorotatory
(C) α and β anomers
(D) Epimers
41. The carbohydrate of the blood group substances is
(A) Sucrose
(B) Fucose
(C) Arabinose
(D) Maltose
42. Erythromycin contains
(A) Dimethyl amino sugar
(B) Trimethyl amino sugar
(C) Sterol and sugar
(D) Glycerol and sugar
43. A sugar alcohol is
(A) Mannitol
(B) Trehalose
(C) Xylulose
(D) Arabinose
44. The major sugar of insect hemolymph is
(A) Glycogen
(B) Pectin
(C) Trehalose
(D) Sucrose
45. The sugar found in DNA is
(A) Xylose
(B) Ribose
(C) Deoxyribose
(D) Ribulose
46. The sugar found in RNA is
(A) Ribose
(B) Deoxyribose
(C) Ribulose
(D) Erythrose
47. The sugar found in milk is
(A) Galactose
(B) Glucose
(C) Fructose
(D) Lactose
48. Invert sugar is
(A) Lactose
(B) Sucrose
(C) Hydrolytic products of sucrose
(D) Fructose
49. Sucrose consists of
(A) Glucose + glucose
(B) Glucose + fructose
(C) Glucose + galactose
(D) Glucose + mannose
50. The monosaccharide units are linked by 1 → 4 glycosidic linkage in
(A) Maltose
(B) Sucrose
(C) Cellulose
(D) Cellobiose
Answers
