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pharmacy Topic wise MCQs

Biochemistry ( Part- 6 ) MCQs with Answers

BIOCHEMISTRY

51. Vitamin required for the conversion of phydroxyphenylpyruvate to homo-gentisate is
(A) Folacin
(B) Cobalamin
(C) Ascorbic acid
(D) Niacin

52. Vitamin required in conversion of folic Acid to folinic acid is
(A) Biotin
(B) Cobalamin
(C) Ascorbic acid
(D) Niacin

53. Ascorbic acid can reduce
(A) 2, 6-Dibromobenzene
(B) 2, 6-Diiodoxypyridine
(C) 2, 6-Dichlorophenol indophenol
(D) 2, 4-Dinitrobenzene

54. Sterilised milk lacks in
(A) Vitamin A
(B) Vitamin D
(C) Vitamin C
(D) Thiamin

55. Scurvy is caused due to the deficiency of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin K
(D) Vitamin C

56. Both Wernicke’s disease and beriberi can be reversed by administrating
(A) Retinol
(B) Thiamin
(C) Pyridoxine
(D) Vitamin B12

57. The Vitamin B1 deficiency causes

  1. (A) Ricket
  2. (B) Nyctalopia
  3. (C) Beriberi
  4. (D) Pellagra

58. Concentration of pyruvic acid and lactic acid in blood is increased due to deficiency of the vitamin
(A) Thiamin
(B) Riboflavin
(C) Niacin
(D) Pantothenic acid

59. Vitamin B1 coenzyme (TPP) is involved in
(A) Oxidative decarboxylation
(B) Hydroxylation
(C) Transamination
(D) Carboxylation

60. Increased glucose consumption increases The dietary requirement for
(A) Pyridoxine
(B) Niacin
(C) Biotin
(D) Thiamin

61. Thiamin is oxidized to thiochrome in Alkaline solution by
(A) Potassium permanganate
(B) Potassium ferricyanide
(C) Potassium chlorate
(D) Potassium dichromate

62. Riboflavin is a coenzyme in the reaction Catalysed by the enzyme
(A) Acyl CoA synthetase
(B) Acyl CoA dehydrogenase
(C) β-Hydroxy acyl CoA
(D) Enoyl CoA dehydrogenase

63. The daily requirement of riboflavin for adult in mg is
(A) 0–1.0
(B) 1.2–1.7
(C) 2.0–3.5
(D) 4.0–8.0

64. In new born infants phototherapy may Cause hyperbilirubinemia with deficiency of
(A) Thiamin
(B) Riboflavin
(C) Ascorbic acid
(D) Pantothenic acid

65. Riboflavin deficiency causes
(A) Cheilosis
(B) Loss of weight
(C) Mental deterioration
(D) Dermatitis

66. Magenta tongue is found in the deficiency Of the vitamin
(A) Riboflavin
(B) Thiamin
(C) Nicotinic acid
(D) Pyridoxine

67. Corneal vascularisation is found in deficiency of the vitamin:
(A) B1
(B) B2
(C) B3
(D) B6

68. The pellagra preventive factor is
(A) Riboflavin
(B) Pantothenic acid
(C) Niacin
(D) Pyridoxine

69. Pellagra is caused due to the deficiency of
(A) Ascorbic acid
(B) Pantothenic acid
(C) Pyridoxine
(D) Niacin

70. Niacin or nicotinic acid is a monocarboxylic acid derivative of

  1. (A) Pyridine
  2. (B) Pyrimidine
  3. (C) Flavin
  4. (D) Adenine

71. Niacin is synthesized in the body from

  1. (A) Tryptophan
  2. (B) Tyrosine
  3. (C) Glutamate
  4. (D) Aspartate

72. The proteins present in maize are deficient in

  1. (A) Lysine
  2. (B) Threonine
  3. (C) Tryptophan
  4. (D) Tyrosine

73. Niacin is present in maize in the form of

  1. (A) Niatin
  2. (B) Nicotin
  3. (C) Niacytin
  4. (D) Nicyn

74. In the body 1 mg of niacin can be produced from
(A) 60 mg of pyridoxine
(B) 60 mg of tryptophan
(C) 30 mg of tryptophan
(D) 30 mg of pantothenic acid

75. Pellagra occurs in population dependent on
(A) Wheat
(B) Rice
(C) Maize
(D) Milk

76. The enzymes with which nicotinamide act As coenzyme are

  1. (A) Dehydrogenases
  2. (B) Transaminases
  3. (C) Decarboxylases
  4. (D) Carboxylases

77. Dietary requirement of Vitamin D:

  1. (A) 400 I.U.
  2. (B) 1000 I.U.
  3. (C) 6000 I.U.
  4. (D) 700 I.U.

78. The Vitamin which does not contain a ring In the structure is

  1. (A) Pantothenic acid
  2. (B) Vitamin D
  3. (C) Riboflavin
  4. (D) Thiamin

79. Pantothenic acid is a constituent of the Coenzyme involved in

  1. (A) Decarboxylation
  2. (B) Dehydrogenation
  3. (C) Acetylation
  4. (D) Oxidation

80. The precursor of CoA is

  1. (A) Riboflavin
  2. (B) Pyridoxamine
  3. (C) Thiamin
  4. (D) Pantothenate

81. ‘Burning foot syndrome’ has been ascribed to the deficiency of

  1. (A) Pantothenic acid
  2. (B) Thiamin
  3. (C) Cobalamin
  4. (D) Pyridoxine

82. Pyridoxal phosphate is central to

  1. (A) Deamination
  2. (B) Amidation
  3. (C) Carboxylation
  4. (D) Transamination

83. The vitamin required as coenzyme for the action of transaminases is

  1. (A) Niacin
  2. (B) Pantothenic acid
  3. (C) Pyridoxal phosphate
  4. (D) Riboflavin

84. Vitamin B6 deficiency may occur during therapy with

  1. (A) Isoniazid
  2. (B) Terramycin
  3. (C) Sulpha drugs
  4. (D) Aspirin

85. Deficiency of vitamin B6 may occur in

  1. (A) Obese person
  2. (B) Thin person
  3. (C) Alcoholics
  4. (D) Diabetics

86. ‘Xanthurenic acid index’ is a reliable criterion for the deficiency of the vitamin

  1. (A) Pyridoxal
  2. (B) Thiamin
  3. (C) Pantothenic acid
  4. (D) Cobalamin

87. Epileptic form convulsion in human infants have been attributed to the deficiency of the vitamin

  1. (A) B1
  2. (B) B2
  3. (C) B6
  4. (D) B12

88. Biotin is a coenzyme of the enzyme

  1. (A) Carboxylase
  2. (B) Hydroxylase
  3. (C) Decarboxylase
  4. (D) Deaminase

89. The coenzyme required for conversion of pyruvate to oxaloacetate is

  1. (A) FAD
  2. (B) NAD
  3. (C) TPP
  4. (D) Biotin

90. In biotin-containing enzymes, the biotin is bound to the enzyme by
(A) An amide linkage to carboxyl group of glutamine
(B) A covalent bond with CO2
(C) An amide linkage to an amino group of lysine
(D) An amide linkage to α-carboxyl group of Protein

91. A molecule of CO2 is captured by biotin when it acts as coenzyme for carboxylation reaction. The carboxyl group is covalently attached to
(A) A nitrogen (N1) of the biotin molecule
(B) Sulphur of thiophene ring
(C) α-Amino group of lysine
(D) α-Amino group of protein

92. Consumption of raw eggs can cause deficiency of
(A) Biotin
(B) Pantothenic acid
(C) Riboflavin
(D) Thiamin

93. The cofactor or its derivative required for the conversion of acetyl CoA to malonyl-CoA is

  1. (A) FAD
  2. (B) ACP
  3. (C) NAD+
  4. (D) Biotin

94. A cofactor required in oxidative decarboxylation of pyruvate is
(A) Lipoate
(B) Pantothenic acid
(C) Biotin
(D) Para aminobenzoic acid

95. The central structure of B12 referred to as corrin ring system consists of

  1. (A) Cobalt
  2. (B) Manganese
  3. (C) Magnesium
  4. (D) Iron

96. The central heavy metal cobalt of vitamin B12 is coordinately bound to
(A) Cyanide group
(B) Amino group
(C) Carboxyl group
(D) Sulphide group

97. Vitamin B12 has a complex ring structure (Corrin ring) consisting of four

  1. (A) Purine rings
  2. (B) Pyrimidine rings
  3. (C) Pyrrole rings
  4. (D) Pteridine rings

98. Emperical formula of cobalamin is
(A) C63H88N12O14 P.CO
(B) C61H82N12O12 P.CO
(C) C61H88N12O14 P.CO
(D) C63H88N14O14 P.CO

99. A deficiency of vitamin B12 causes
(A) Beri-Beri
(B) Scurvy
(C) Perniciuos anemia
(D) Ricket

100. Vitamin B12 deficiency can be diagnosed by urinary excretion of

  1. (A) Pyruvate
  2. (B) Methylmalonate
  3. (C) Malate
  4. (D) Lactate

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