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Diabetes, and antidiabetic drugs:- PDF/ PPT


A). Diabetes, and antidiabetic drugs
By the completion of this section the learners will be able to:
• Discuss the role of Insulin in metabolic process.
• Discuss different types of anti-diabetic agents with their mode of action, side effects and care.
• List the principles of therapy for all anti-diabetic agents.
• State reasons for combinations of insulin and oral hypoglycemic agents.
• Calculate drug dosage accurately.
• Diabetes Mellitus
• Types of Diabetes Mellitus
• New-onset diabetes after transplantation (NODAT)
• Glucose transporters
• Classification of Anti diabetic drugs
• Miscellaneous antidiabetic drugs
• Insulin
• Cell Organization in Pancreas
• Cell Types in the Pancreatic Islets
• Insulin discovery
• Release of insulin from beta cells
• How Insulin act ?
• Mechanism of insulin
• Adverse reactions to insulin
• Reactions to insulin
• Glucagon-like Polypeptide-1 (GLP-1) Receptor agonists
Incretin mimetics
• What is Dipeptidyl peptidase-IV (DPP-IV) ?
• What is incretin effect?
• Incretin mimetics
• Mechanism of action
• Exenatide (Byetta®) Adverse effects
• Oral Anti-diabetic Drugs
• Dipeptidyl peptidase 4 inhibitors
• Mechanism of action DPP-4 Inhibitors
• Sulfonylureas
• Mechanism of action of sulfonylureas
• Sulfonylureas mechanism of action
• Adverse effects of sulfonylureas
• Meglitinides/Glinides
• Biguanides
• Thiazolidinedione’s
• α-Glucosidase inhibitors
• Sodium–glucose cotransporter 2 inhibitors
• Sodium–glucose cotransporter 2 inhibitors Adverse effects
• Principles of treatment with antihyperglycemic agents

  • Subject:- Pharmacology
  • Course:- B.pharm (pharmacy),
  • Semester:- 5th sem , sem :- 5