1. Glibenclamide belongs to the class
a. Sulphonyl ur eas
b. Thiazolidinediones
c. Benzoic acid derivatives
d. Biguanides
2. Repaglinide belongs to the class
a. Sulphonyl ur eas
b. Thiazolidinediones
c. Benzoic acid derivatives
d. Biguanides
3. The antidiabetic also effective in lowering the cholesterol level is
a. Rosiglitazone
b. Phenformin
c. Chlorpropamide
d. Repaglinide
4. The mechanism of action of rosiglitazone is
a. Insulin-releasing agent
b. PPARγ agonist
c. Increases cellular uptake of glucose
d. Reduces release of insulin
5. The terminal nitrogen in sulphonyl ureas should be substituted with
a. At least 2 carbon chain
b. At least 3 carbon chain
c. At least 12 carbon chain
d. At least 1 aryl unit
Answers key
1. a 2. c 3. a 4. b. 5. b
