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Local Anaesthetics MCQs With Answers

1. Which of the following local anaesthetics is least associated with dermatitis and asthma?

screenshot 20210907 1529053976925014644444375 Local Anaesthetics MCQs With Answers

2. Which of the following statements is a characteristic of an ideal local anaesthetic?
a. It should be reversible in action.
b. It should be effective when used both systematically and topically.
c. It should have maximum irritation either topically or at the site of injection.
d. All of the above.

3. The starting material for the synthesis of dibucaine is
a. 4-Chloroacetophenone
b. Isatin
c. Indole
d. 2-Formyl benzoic acid

4. One of the following is true of anilide as local anaesthetics:
a. Phenyl group is attached to the sp 3
c arbon atom.
b. The methyl substituent provide steric
hindrance to hydrolysis of the amide
c. Substitution of the phenyl with a methyl group reduces activity.
d. All of the above.

5. Anaesthesia of mucous membranes is called
a. Inltration anaesthesia
b. Field block anaesthesia
c. Nerve block anaesthesia
d. Topical analgesia

6. One of the following drugs does not belong to the benzoic acid class of anaesthetics:
a. Benzocaine
b. Cocaine
c. Piperocaine
d. Hexylcaine

7. One of the following does not contain the piperidine moiety in its structure:
a. Mepivacaine
b. Cyclomethycaine
c. Lidocaine
d. Bupivacaine

8. The drug that was discovered accidentally while research actually aimed for the preparation of antimalarial agents related to quinine
a. Quinacrine
b. Dibucaine
c. Dimethisoquin
d. Benoxinate

9. The following drug synthesis involves Mannich reaction in one of the steps:
a. Dibucaine
b. Diclonine
c. Lidocaine
d. Diperodone

Answers Key

1. a
2. d
3. b
4. b
5. d
6. a
7. c
8. b
9. b
10. d