Description
Morphine
• Pharmacokinetics of Morphine
• Mechanism of action of Morphine
• Actions of Morphine
• ADRs of Morphine
• Tolerance and physical dependence
• Drug interactions
• Atropine
• Pharmacokinetics of Atropine
• Pharmacodynamics of Atropine
• Actions of Atropine
• Therapeutic uses of Atropine
• ADRs of Atropine
Atropine
• Atropine is a naturally occurring tropane alkaloid extracted from deadly nightshade (Atropa belladonna), Jimson weed (Datura stramonium) and other plants of the family Solanaceae. It is a secondary
metabolite of these plants and serves as a drug with a wide variet of effects.
• Class of Drug: Anticholinergic or Antiparasympathetic
(Parasympatholytic) Drug.
• • Bioavailability : 25% (oral); 100% (IV)
• Protein binding: 30–40%
• Metabolism: Hepatic 90%
• Half life: 2–3 h
• Excretion: Renal 90%, biliary 10%
• Therapeutic considerations Pregnancy cat C
• Routes: Smoked/inhaled, insufflated, SC, IM, IV.
- Subject:- pharmacology 3
- Course:- B.pharm (pharmacy),
- Semester:- 5th sem , sem :- 5
