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Pathophysiology (BP304TP) Question list

B.Pharm Sem-3
Pathophysiology (BP304TP)

  1. Basic principal of cell injury and adaptation.
  2. Underlying changes in biochemical system of cells for irreversible cell injury.
  3. Etiology of cell injury
  4. Pathological Changes in Apoptosis
  5. Cause and pathology underlying atrophy.
  6. Note: Tissue regeneration process
  7. Mechanism of cell injury
  8. Define apoptosis and mechanism of apoptosis
  9. Explain cellular and molecular mechanism of reversible and irreversible cell injury due to
    hypoxia and ischemia
  10. Apoptosis. Write cause, mechanism and importance.
  11. Define and classify cellular adaptations. Write the causes of atrophy and hyperplasia.
  12. Detail the process of Phagocytosis
  13. Define necrosis. Give its types and associated morphological changes.
  14. Write a note on free radical mediated cell injury.
  15. Define atrophy. Enlist the physiological and pathological causes of atrophy.
  16. Write causes of cell injury. Explain acquired causes of cell injury.
  17. Differentiate term atrophy ad hypertrophy. Explain pathologic hypertrophy.
  18. Write in detail about cellular adaptations.
  19. Define necrosis. Give its type and associated morphological changes.
  20. Give the aetiology of Cell Injury.
  21. Enumerate the principal Cellular Adaptive Responses. Discuss morphological features of
    Hypertrophy and give its physiological and pathological causes.
  22. Explain Terms
    Natural killer cell, Dendritic cell, Hypertrophy, Atrophy, Hyperplasia, Necrosis,
    Metaplasia, Autophagy
  23. Difference between:
    a. Apoptosis and Necrosis
    b. Chemotaxis and Phagocytosis
  24. Enumerate cell and plasma derived inflammatory mediators. Describe the role of
    different systems in generation of plasma derived mediators
  25. Enlist the various inflammatory cells and discuss their role in inflammation
  26. Discuss the etiology and pathogenesis of B-cell mediated hypersensitivity reactions with suitable examples.
  27. Discuss the role of cytokines and free radicals in different phase of inflammation.
  28. Vascular events in acute inflammation
  29. Define acute inflammation. Write in detail about cell events occur in acute inflammation.
  30. Write in detail about stimuli for acute inflammation.
  31. Write in detail about cell derived mediators of inflammation.
  32. Explain the mechanism of increased vascular permeability in acute inflammation
  33. Enumerate chemical mediators of inflammation and detail their reactions.
  34. Enlist the chemical mediators of inflammation and write a note on plasma derived
  35. mediators.
  36. Describe the process of exudation of leucocytes in the cellular events of acute
  37. inflammation.
  38. Define inflammation. Explain the hemodynamic changes that take place in 05 the
  39. vascular events of acute inflammation.
  40. Explain in brief about granulomatous inflammation.
  41. Write in detail about vascular events of acute inflammation.
  42. Explain the process of wound healing.
  43. Enumerate the types of hypersensitivity reactions. Explain about pathogenesis of B-cell
  44. mediated hypersensitivity reactions.
  45. Explain sequence of events in primary skin wounds. How does the secondary union of skin wounds differ from primary union?
  46. Note: Atherosclerosis
  47. Difference between: Acute and Chronic inflammation
  48. Define anemia. Classification of anemia and Pathophysiology of Iron deficiency anemia
  49. Discuss Pathophysiology of megaloblastic anemia
  50. Describe Pathophysiology Scikle cell anemia Note: Thalasemia
  51. Define Diabetes. Types of diabetes. Pathophysiology of diabetes
  52. Detail pathophysiology of thyroid disorders
  53. Define Epilepsy. Classification of epilepsy. Pathophysiology of epilepsy.
  54. Describe Pathophysiology Parkinson’s disease.
  55. Detail Pathophysiology of Alzheimer’s disease
  56. Write Etiology, patho of peptic ulcer.
  57. Write note on inflammatory bowel syndrome.
  58. Enlist types of hepatitis. Explain in detail pathophysiology of hepatitis.
  59. Write a detail note on jaundice.
  60. Explain pathophysiology of osteoporosis.
  61. Give etiology and pathophysiology of cancer.
  62. Write in detail pathophysiology of rheumatoid arthritis and gout.
  63. Explain in detail about alcoholic liver disease.
  64. Write Detail note on pathophysiology of TB.
  65. Write Detail note on pathophysiology Typhoid
  66. Write in detail pathophysiology of meningitis.
  67. Write in detail pathophysiology of leprosy.
  68. Write in detail pathophysiology of urinary tract infections.
  69. Discuss the pathogenesis, clinical manifestations and diagnosis of AIDS.
  70. How is HIV transmitted? Discuss the pathogenesis and clinical manifestations of AIDS
  71. Give pathophysiology of Syphilis.
  72. Give pathophysiology of Gonorrhea.

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