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pharmacy Topic wise MCQs

Pharmacodynamics: Mechanisms of Drug Action MCQs

Pharmacodynamics: Mechanisms
of Drug Action

1. Which drug-binding receptors cause rapid depolarization or hyperpolarization of cells?
a. Receptors that have enzyme activity on their cytoplasmic side.
b. Intracellular nuclear receptors.
c. Ligand-gated ion channels.
d. G protein-linked receptors.

2. The nicotine drug-binding receptor is an example of a/an
a. enzyme.
b. nucleic acid.
c. ligand-gated ion channel.
d. voltage-gated ion channel.

3. Drug receptors are usually found in which part of a cell?
a. Nucleus.
b. Cytoplasm.
c. Plasma membrane.
d. Mitochondria.

4. Which drug-binding force is the weakest?
a. Ionic.
b. Covalent.
c. Hydrogen.
d. van der Waals.

5. Which drug-binding force complicates the administration and treatment of adverse reactions from a drug?
a. Ionic.
b. Covalent.
c. Hydrogen.
d. van der Waals.

6. Which voltage-gated ion carries a negative charge?
a. K.
b. Cl.
c. Ca.
d. Na.

7. Along with the drug and its receptor, which drug-binding force involves water?
a. Ionic.
b. Covalent.
c. Hydrogen.
d. van der Waals.

8. Which factor supports specificity in drug receptor binding?
a. Differences of optical isomers.
b. Similarities of optical isomers.
c. Whether a drug is a full agonist or a partial agonist.
d. Whether or not the drug has high potency.

9. Which statement is true?
a. The optical isomer quinidine (dextro) has been used therapeutically, but quinine (levo) has not.
b. The optical isomer quinine (levo) has been used therapeutically, but quinidine (dextro) has not.
c. Optical isomers quinine (levo) and quinidine (dextro) have both been used therapeutically, for the same purposes.
d. Optical isomers quinine (levo) and quinidine (dextro) have both been used therapeutically, but for different purposes.

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