Description
Skeletal Muscle Relaxants
• • Discuss common symptoms/disorders for which skeletal muscle relaxants are used.
• Describe uses and effects of skeletal muscle relaxants.
• Differentiate between centrally acting and peripherally acting muscle relaxants
• Describe non-pharmacologic interventions to relieve muscle spasm and spasticity.
• Apply the nursing process with clients experiencing muscle spasm or spasticity.
• Calculate the drug dosages accurately.
• Skeletal Muscle Relaxants (SMRs)
• Common Symptoms/Conditions in which SMRs are used
• History: From Fun hunting in Jungles to Operation theatre
• Neuromuscular Junction (NMJ)
• Physiology of Skeletal Muscle Contraction
• Classification of SMRs
• Classification: Peripherally acting SMRs
• Nondepolarizing (Competitive) blockers
• Nondepolarizing (Competitive) blockers Mechanism of Action
• Nondepolarizing (Competitive) blockers Pharmacological actions:
• Pharmacological actions
• Nondepolarizing blockers – Individual compounds
• Depolarizing Blockers – Succinylcholine
• Mechanism of Action: Succinylcholine
• Advantages of Succinylcholine
• Side effects of Succinylcholine
• What is Malignant hyperthermia
• Indication of Neuro Muscular Junction Blockers
• Directly acting relaxants – Dantrolene
• MOA: Centrally acting Muscle relaxants
• Centrally acting Muscle relaxants
• Mephenesin (Relaxyl/medicreme)
• Benzodiazepines as muscle relaxant
• Baclofen- GABAB agonist
• Tizanidine/ clonidine
• Uses of Centrally acting relaxants
• Centrally acting Vs Peripherally acting
• Non-pharmacologic interventions to relieve muscle spasm and spasticity
• Nursing Role
- Subject:- Pharmacology
- Course:- B.pharm (pharmacy),
- Semester:- 5th sem , sem :- 5
