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Nursing pharmacy Topic wise MCQs

The Female Genital Tract MCQs with Answers

1. The following vulval lesion can progress to vulval carcinoma:

  1. A. Stromal polyp
  2. B. Papillary hidradenoma
  3. C. Squamous hyperplasia
  4. D. Lichen sclerosus

2. High risk HPV types implicated in cervical intraepithelial lesions are:

  1. A. 6 and 11
  2. B. 5 and 8
  3. C. 16 and 18
  4. D. 19 and 22

3. The most common histologic type of cervical cancer is:
A. Well-differentiated keratinising squamous cell carcinoma
B. Moderately-differentiated non-keratinising squamous cell carcinoma
C. Small cell undifferentiated carcinoma
D. Adenocarcinoma

4. Arias-Stella reaction occurs in:
A. Ectopic tubal gestation only
B. All ectopic gestations
C. Uterine gestation
D. Uterine as well as ectopic gestations

5. Chocolate cyst of the ovary is:

  1. A. Haemorrhagic corpus luteum
  2. B. Ruptured luteal cyst
  3. C. Endometriotic cyst
  4. D. Ruptured follicular cyst

6. The malignant potential of atypical hyperplasia is:

  1. A. About 5%
  2. B. About 25%
  3. C. About 50%
  4. D. About 75%

7. Peak incidence of endometrial adenocarcinoma is in:

  1. A. Reproductive years
  2. B. Premenopausal years
  3. C. Perimenopausal years
  4. D. Postmenopausal years

8. The commonest site for endometriosis is:

  1. A. Hernial sacs
  2. B. Vulve
  3. C. Ovaries
  4. D. Vagina

9. Bilaterality of following ovarian tumours is most common:
A. Benign serous tumours
B. Malignant serous tumours
C. Benign mucinous tumours
D. Brenner tumour

10. The most common germ cell tumour of the ovary is:
A. Dysgerminoma
B. Benign teratoma
C. Immature teratoma
D. Endodermal sinus tumour

11. The most aggressive ovarian germ cell tumour is:

  1. A. Malignant teratoma
  2. B. Embryonal carcinoma
  3. C. Endodermal sinus tumour
  4. D. Dysgerminoma

12. Granulosa cell tumour is associated with following except:
A. Endometrial hyperplasia
B. Endometrial adenocarcinoma
C. Endometrioid tumour
D. Fibrocystic change in breast

13. Krukenberg tumour is bilateral metastatic tumour from the following primary sites except:

  1. A. Stomach
  2. B. Colon
  3. C. Breast
  4. D. Endometrium

14. The following trophoblastic tumour does not respond to chemotherapy:

  1. A. Complete mole
  2. B. Invasive mole
  3. C. Gestational choriocarcinoma
  4. D. Ovarian choriocarcinoma

15. Identifiable chorionic villi are present in the following tumours except:
A. Complete mole
B. Partial mole
C. Invasive mole
D. Gestational choriocarcinoma

16. According to the Bethesda system, the squamous intraepithelial lesions for the grades of cervical cytology are:

  1. A. Two
  2. B. Three
  3. C. Four
  4. D. Five

17. In the etiology of condyloma acuminatum, the most commonly implicated HPV types are:

  1. A. Types 1,2
  2. B. Types 6, 11
  3. C. Types 2,3,9
  4. D. Types 16,18

18. Protein product of HPV 16 is:

  1. A. E2
  2. B. E5
  3. C. E6
  4. D. E7

19. Upper age limit for cervical screening is:

  1. A. 50 years
  2. B. 55 years
  3. C. 60 years
  4. D. None

20. Characteristic mutation seen in endometrioid carcinoma is:

  1. A. PTEN
  2. B. p53
  3. C. Rb
  4. D. K-ras

21. Genetic syndrome associated with increased risk of ovarian cancer includes all except:
A. Lynch syndrome
B. Peutz-Jegher’s syndrome
C. Nevoid basal cell carcinoma
D. Turcot’s syndrome

22. Pick the odd one out:
A. Sertoli-Leydig cell tumour
B. Androblastoma
C. Arrhenoblastoma
D. Gonadoblastoma

23. A 60 years old woman reports to physician for progressive fatigue, loss of appetite and malaise for the last 2 months. An upper GI endoscopy reveals an ulcerative mass located along the lesser curvature. CT scan of the abdomen shows bilateral ovarian masses. Which of the following condition this patient is most likely to have?
A. Ampullary carcinoma
B. Krukenberg tumour
C. Serous adenocarcinoma of the ovary
D. Endometrioid carcinoma of the uterine body

24. Pap smear of a 30 years old woman is found to have atypical cells suggestive of HPV infection. Which of the following abnormalities describes the characteristic cytologic feature caused by HPV infection in Pap smear?

  1. A. Acanthosis
  2. B. Parakeratosis
  3. C. Hyperkeratosis
  4. D. Koilocytosis

Answers Key
1) = C, 2) = C, 3) = B, 4) = D, 5) = C, 6) = B, 7) = D, 8) = C, 9) = B, 10) = B, 11) = B, 12) = C, 13) = D, 14) = D, 15) = D, 16) = A, 17) = B, 18) = D, 19) = D, 20) = A, 21) = D, 22) = D, 23) = B, 24) = D

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