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Therapuetic Drug Monitoring Of Digoxin

THERAPUETIC DRUG MONITORING
OF DIGOXIN

CASE STUDY:
A woman of 65kg and height of 160cm(5ft,3inches) who is 50yrs old with acute atrial fibrillation.Her serum creatinine is 100umol/l.Caculate IV loading and oral maintainence dose.
HINTS:
Calculate IBW,Vd,Clcr
SOLUTION:
Height = 160cm (5ft,3inches)
Weight = 65kg
IBW = 45.5 + [2.3*HIEGHT IN INCHES OVER 5FT]
= 45.5 +[2.3*3]
=52.4

Vd =3.128 * Clcr +3.84 8 52.4
To find creatinne clearance;

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