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What is anti-neoplastic agent and thare classification.

Definition:-

Antineoplastic or anticancer drugs are used for treating malignancies or cancerous growths. Either these drugs are used alone (chemotherapy) or in combination with surgery or radiation therapy.

The anti-neoplastic agents are classified as follows:

1) Alkylating agents

Nitrogen mustards:- Mechlorethamine (Mustine HCl) , Ifosfamide, Cyclophosphamide, Chlorambucil, and Melphalan
Ethylenimine:- Thiotepa
Alkyl sulfonate:- Busulfan
Nitrosoureas:- Carmustine (BCNU) and Lomustine (CCNU)
Triazine:- Dacarbazine (DTIC)

2) Antimetabolites

Folate antagonist:- Methotrexate (Mtx)
Purine antagonist:- 6-Mercaptopurine (6 -MP), 6-Thioguanine (6 -TG), and Azathioprine
Pyrimidine antagonist:- 5-Fluorouracil (5 -FU) and Cytarabine (cytosine arabinoside)

3) Natural Products

Vinca alkaloids:- Vincristine (Oncovin) and Vinblastine
Taxanes:- Paclitaxel and Docetaxel
Epipodophyllo toxin:- Etoposide
Camptothecin analogues:- Topotecan and Irinotecan

4) Antibiotics

Actinomycin D, Dactinomycin, Doxorubicin, Daunorubicin, Rubidomycin, Mitoxantrone, Bleomycin, Mitomycin C, and Mithramycin

5) Enzymes:-

Asparaginase (Elspar)

6) Miscellaneous

Hydroxyurea, Procarbazine, L -Asparaginase, Cisplatin, and Carboplatin

7) Hormones

Glucocorticoids:- Prednisolone
Estrogens:- Fosfestrol and Ethinylestradiol
Antiestrogen:- Tamoxifen
Antiandrogen:- Flutamide
5- reductase inhibitor:- Finasteride
GnRH analogues:- Nafarelin and Goserelin
Progestins:- Hydroxyprogesterone Acetate, etc.

8) Radioactive Isotopes

Sodium phosphate, Sodium iodide , and Radio gold solution

anti-neoplastic agents classification in Table format

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