Remix education

What is anti-neoplastic agent and thare classification.


Antineoplastic or anticancer drugs are used for treating malignancies or cancerous growths. Either these drugs are used alone (chemotherapy) or in combination with surgery or radiation therapy.

The anti-neoplastic agents are classified as follows:

1) Alkylating agents

Nitrogen mustards:- Mechlorethamine (Mustine HCl) , Ifosfamide, Cyclophosphamide, Chlorambucil, and Melphalan
Ethylenimine:- Thiotepa
Alkyl sulfonate:- Busulfan
Nitrosoureas:- Carmustine (BCNU) and Lomustine (CCNU)
Triazine:- Dacarbazine (DTIC)

2) Antimetabolites

Folate antagonist:- Methotrexate (Mtx)
Purine antagonist:- 6-Mercaptopurine (6 -MP), 6-Thioguanine (6 -TG), and Azathioprine
Pyrimidine antagonist:- 5-Fluorouracil (5 -FU) and Cytarabine (cytosine arabinoside)

3) Natural Products

Vinca alkaloids:- Vincristine (Oncovin) and Vinblastine
Taxanes:- Paclitaxel and Docetaxel
Epipodophyllo toxin:- Etoposide
Camptothecin analogues:- Topotecan and Irinotecan

4) Antibiotics

Actinomycin D, Dactinomycin, Doxorubicin, Daunorubicin, Rubidomycin, Mitoxantrone, Bleomycin, Mitomycin C, and Mithramycin

5) Enzymes:-

Asparaginase (Elspar)

6) Miscellaneous

Hydroxyurea, Procarbazine, L -Asparaginase, Cisplatin, and Carboplatin

7) Hormones

Glucocorticoids:- Prednisolone
Estrogens:- Fosfestrol and Ethinylestradiol
Antiestrogen:- Tamoxifen
Antiandrogen:- Flutamide
5- reductase inhibitor:- Finasteride
GnRH analogues:- Nafarelin and Goserelin
Progestins:- Hydroxyprogesterone Acetate, etc.

8) Radioactive Isotopes

Sodium phosphate, Sodium iodide , and Radio gold solution

anti-neoplastic agents classification in Table format

screenshot 2021 07 21 09 04 59 650 com3495095402418259205 What is anti-neoplastic agent and thare classification.screenshot 2021 07 21 09 06 13 118 com4378368470382243294 What is anti-neoplastic agent and thare classification.