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pharmacy Topic wise MCQs

Formulative Pharmacy MCQs With Answers

Class: Third Year Year Semester: Third
Subject: Formulative Pharmacy

Code : BP502T

1. Preformulation studies helps in establishing ………………… of a new drugs.
A) Physical properties
B) Kinetic rate profile
C) Chemical properties
D) All the above

2. According to BCS, class III drugs are,…………..
A) Low solubility and Low permeability drugs
B) Low solubility and High permeability drugs
C) High solubility and High permeability drugs
D) High solubility and Low permeability drugs

3. Preformulation is about ensuring
A. Stability
B. Safety
C. Efficacy
D. All of the above

4. Crystal form shows this structure
A. 3D
B. 2D
C. Short range
D. None of the above

5. In simple cubic crystal the faces are
A. All unequal
B. Two equal one unequal
C. All equal

6. Two or more molecules are hydrogen bonded to each other are called
A. Crystals

B. Cocrystals
C. Polymorph
D. All of the above

7. DSC is ……………….
A. Differential scanning calorimetry
B. Differential scttering calorimetry
C. Digital scanning calorimetry
D. None of the above

8. X ray diffraction pattern indicate
A. Solubility
B. Crystallinity
C. Functional groups
D. Permeability

9. SEM can analyze ……..
A. Shape & Size
B. Crystallinity & Solubility
C. Complexation
D. Flow property

10. Bragg’s law define the
A. Shape
B. Solubility
C. Diffraction
D. All of the above

11. Crystal form shows
A. Short duration of action
B. Rapid duration of action
C. Short onset of action
D. Long duration of action

12.The ability of a substance to exist as two or more crystalline phases with different arrangements of molecules in crystal lattice is
A. Cocrystal
B. Crystal
C. Polymorphism
D. None of the above

13. Polymorphs differ in
A. Physical properties
B. Chemical Properties
C. A & B both
D. None of the above

14. Hydrates and colvates are called
A. Polymorph
B. Pseudopolymorph
C. Cocrystals
D. None of the above

15. Coulter Counter can analyze
A. Size distribution
B. Crystallinity & Solubility
C. Number of functional groups
D. Flow property

16. Single-station tablet press is also called as
a) Eccentric press
b) Single punch tablet press
c) Both (a) and (b)

d) None of the above

17. Tablet coating is done to………….
a) Mask the unpleasant taste and odour
b) Improve patient acceptability
c) Provide control drug release
d) All of the above

18. Sugar coating increases the tablet weight by…………..
a) 50 – 100%
b) 5-10%
c) 50%
d) 10 – 15%

19. ………………is an example of enteric film former.
a) Cellulose acetate phthalate
b) Hydroxypropyl methyl cellulose
c) Polyethylene glycol
d) Ethylcellulose

20. Rate of sedimentation is high in ………………….
a) Deflocculated suspensions
b) Flocculated suspensions
c) Both (a) and (b)
d) None of the above

21. Emulsifiers act as detergents, when the HLB value is
a) < 10
b) 10
c) < 15
d) > 15

22. …………….are hydroalcoholic solutions of drugs with low water solubility.
a) Linctuses
b) Elixirs
c)Draughts
d) Douches

23. Which of the following can be formulated into hard gelatin capsules?
a) Pellets
b) Powders
c) Granules
d) All of the above

24. The ratio of gelatin to water in capsule shell is
a) 1:1
b) 0.7:1
c) 1: 1.3
d) 0.7:1.3

25. Empty hard gelatin capsules for human use are available in …………different sizes.
a)5
b) 8
C) 3
d) 6

26. Which of the following is not a soft gelatin capsulation process?
a) Vacuum filling

b) Plate process
c) Rotary die process
d) Reciprocating die process

27. Which of the following is the smallest size hard gelatin capsule?
a) 000
b) 00
c) 0
d) None of the above

28. Which among the following is not a screw-feed extruder?
a) Dome extruder
b) Radial feed extruder
c) Rotary gear extruder
d) End plate screw feed extruder

29. ……………..drugs can be processed in RAM extruder.
a) Thermolabile
b) Thermostable
c) Both (a) and (b)
d) None of the above

30. Radial Extruder belongs to ………………….
a) AxiaVend plate screw feed extruders
b) Gravity/roll feed extruders
c) Piston feed extruders/RAM extruders
d) None of the above

31. …………….density extrudate is produced by gravity feed extruder.
a) Higher
b) Lower

c) Both (a) and (b)
d) None of the above

32. Extruders and spheronizers are used to produce,
a) Controlled released pellets for encapsulation
b) Sustained release pellets
c) Multi-particulate systems
d) All of the above

33. ………………….are applied directly to the affected area.
a) Eye drops
b) Eye gels
c) Eye ointments
d) Eye suspensions

34. Eye drops are used in which of the following disorders?
a) Cataract surgery
b) Glaucoma
c) Conjunctivitis
d) All the above

35. Which of the following ophthalmic preparations exhibit higher bioavailability?
a) Eye drops
b) Eye gels
c) Eye ointments
d) Eye suspensions

36. Intracraneal injections are sterile solutions of drugs meant to be injected in
a) Cornea
b) Sclera

c) Vitreous cavity
d) Posterior chamber of eye

37. ………………..facilitates the insertion of the lens comfortably into the eye.
a) Viscosifier
b) Tonicity adjuster
c) Wetting solution
d) Buffering agent

38. Filtration sterilization is suitable for…………..
a) Ophthalmic and parenteral solutions
b) Antibiotic solutions
c) Blood components
d) All of the above

39. ……………….are the most commonly used eye lotions.
a) Sodium chloride eye lotion
b) Sodium bicarbonate eye lotion
c) Both (a) and (b)
d) None of the above

40.…….are used to soothen, refresh and remove redness of eye due to minor irritation.
a) Cycloplegics
b) Artificial tears
c) Decongestants
d) None of the above

41. ……..helps in improving or changing the appearance of the body and also masks the odour
a) Accessories
b) Cosmetics
c) Clothes
d) None of the above

42. ………are used for the purpose of removing make-up, surface grime and secretions of
the neck respectively.
a) Vanishing creams
b) Hand creams
c) Cleansing and cold creams
d) Body creams

43. ……………..are semisolid emulsions containing mixtures of oil and water.
a) Creams
b) Lotions
c) Powders
d) Rouges

44. Whitening agent used in the formulation of tooth paste is ………………..
a) Calcium carbonate
b) Titanium dioxide
c) Chlorhexidine
d) Methyl paraben

45. ……………..helps in expelling the contents from the aerosol container.
a)Valves
b) Actuators

c) Ferrule
d) Spring

46. Steroids and antibiotics are formulated and dispensed by………… foam systems.
a) Non-aqueous stable
b) Stable-aqueous
c) Aqueous stable
d) Thermal

47. ………………helps in dispensing active ingredient in the form of mist or spray.
a) Foam system
b) Aqueous stable system
c) Aquasol system
d) Intranasal system

48. Which of the following is similar to threaded screw-on closures?
a) Lug closure
b) Press-on closure
c) Plug- type closures
d) Roll-on closures

48. The process of dry granulation involves initial conversion of powder tablet blend into …………………. or …………….. .
a) Slug, Compact masses
b) Damp, coherent mass
c) Hard, compressed mass
d) smooth, shining

49. Which of the following is the smallest size hard gelatin capsule?

a) 5
b) 00
c) 000
d) None of the above

50. Angle of repose is given by
a) ø =tan -1 (H/R)
b) ø =tan (H/R)
c) ø =tan -1(R/H)
d) ø =tan (R/H)

51. ………………………….. studies are carried out prior to the actual formulation of the drug.

a) Preformulation
b) Bioavailability
c) Clinical
d) Bioequivalence

52. Preformulation studies helps in establishing ……………………… of a new drugs.
a) Physical properties
b) Kinetic rate profile
c) Chemical properties
d) All the above

53. According to BCS, class II drugs are,
a) Low solubility and Low permeability drugs
b) Low solubility and High permeability drugs
c) High solubility and High permeability drugs
d) High solubility and Low permeability drugs

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54. According to BCS, class III drugs are,
a) Low solubility and Low permeability drugs
b) Low solubility and High permeability drugs
c) High solubility and High permeability drugs
d) High solubility and Low permeability drugs

55. According to BCS, class I drugs are,
a) Low solubility and Low permeability drugs
b) Low solubility and High permeability drugs
c) High solubility and High permeability drugs
d) High solubility and Low permeability drugs

56. ……………….. and ………………. Collectively gives a measure of the tablet
strength.
a) Friability, Hardness
b) Dimensions, Hardness
c) Friability, Dissolution
d) Dissolution, Hardness

57. The biopharmaceutics classification system is based on ………………….. of a drug
substances.
a) Solubility
b) Permeability
c) Dissolution rate
d) All the above

58. Rate of sedimentation is high in ………………………. .
a) Deflocculated suspensions
b) Flocculated suspensions
c) Both (a) and (b)
d) None the above

59. Type I glass is …………….
A) Soda lime
B) Treated soda lime
C) Borosilicate glass
D) None of the above

60. Higher HLB values (9-12) of emulsifying agents produce …. Type of emulsion.
A) Oil in Water
B) Water in Oil
C) Both A and B
D) None of the above

61. In deflocculated suspensions, …………………… of particles is difficult.
A) Redispersion
B) stabilization
C) Both (a) and (b)
D) None the above

62. ………….. studies are carried out prior to the actual formulation of the drug.
A) Bioequivalence
B) Bioavailability
C) Clinical
D) Preformulation

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