Remix education
pharmacystudy material

Geometrical isomerism (unit:-2):- Hand written notes


  • Geometrical isomerism
  • Nomenclature of geometrical isomers
  • (Cis Trans, EZ, Syn Anti systems)
  • Methods of determination of configuration of geometrical isomers.
  • Conformational isomerism in Ethane,
  • n-Butane and Cyclohexane.
  • Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity.
  • Stereospecific and stereoselective reactions

Important Question unit 2 organic chemistry

1). Differentiate stereoselective and stereospecific reactions.
2). Give short notes on nomenclature of geometrical isomers.
3). Discuss stability of various conformations of cyclohexane.
4). Discuss stability of various conformations of n-butane.
5). Explain stereoisomerism in biphenyl compounds.
6). Draw structure of the following compounds.
i) cis-3,4-dimethyl-3-heptene ii) trans-1,3-dichlorocyclobutane
iii) (R)-2-butanol iv) (RS)-2-chloro, 3-pentanol
v) cis- 2-chloro,3-bromo butene vi) (S)-3-chlorohexane
7). Explain diastereomers and their properties with suitable example.
8). Explain the stereospecific and stereoselective reactions.
9). Give methods of determination of configuration of geometrical isomers.
10). Give brief note on Conformation of Cyclohexane.
11). State and Explain
d) Mesomers e) Geometric Isomer
12). Write a Short Note on Geometric Isomerism.
13). State and Explain and give brief note on Atropisomers with suitable examples.
14). Explain in brief with suitable example – Stereospecific and Stereoselective reactions.

  • Subject:- Pharmacutical organic chemistry 3
  • Course:- B.pharm (pharmacy),
  • Semester:- 4th sem , sem :- 4