Multidrug therapy (MDT) is the treatment of choice for all leprosy patients. It entails the swallowing of a combination of anti-leprosy drugs on a daily basis, in the recommended doses for the recommended duration of treatment and according to the WHO leprosy classification.
In 1981, the WHO developed, by consensus, a multidrug therapy (MDT) with dapsone and rifampin for 6 to 12 months for paucibacillary (PB) while clofazimine was added and the length of therapy extended to 24 months for multibacillary (MB) leprosy [5].20-Jan-2020
The drugs used in MDT leprosy treatment are rifampicin (R), dapsone (D) and clofazimine (C).