Pharmaceutical Technology- 2 MCQs with Answers
1. Which one of these is responsible for hardness of tablet?
a) Die Filling
b) Compression force
c) Both (a) & (b)
d) None of these
Ans. : C
2. Crown thickness of the tablet is measured by
a) Micrometer
b) Hydrometer
c) Pychnometer
d) Any one of the above
Ans.: C
3. Friablilator is operated for _________ revolutions per minute.
a) 100
b) 75
c) 50
d) 25
Ans.: A
4. In dissolution test, flask is maintained at:
a) 31° C ± 0.5C
b) 41° C ± 0.1C
c) 39° C ± 0.6C
d) 40° C ± 0.1C
Ans. : A
5. Enteric coated tablet disintegrate in ____ hrs in simulated intestinal fluid.
a 1
b) 2
c) 3
d) 4
Ans.: B
6. Separation of tablet in 2 or more distinct layer is
a) Capping
b) Mottling
c) Lamination
d) Air entrapment
Ans.: C
7. Capping is prevented by using:
a) Flat
b) Circular
c) Square
d) Rectangular
Ans.: A
8. Plating of punch forces is done by:
a) Chromium
b) Zinc
c) Iron
d) Any of the above
Ans.: A
9. Unequal distribution of color is called
a) Capping
b) Lamination
c) Mottling
d) None of the above
Ans.: C
10. ________ is directly compressible excipient
a) Spray Dried lactose
b) Dibasic calcium phosphate
c) None of the above
d) Any of the above
Ans.: A
11. Sta-Rx-1500 contain ______ % of moisture
a) 15
b) 10
c) 18
d) 50
Ans.: B
12. pH of small intestine is
a) 1-2
b) 3-4
c) 6
d) 7-8
Ans. : D
13. Perforated pan is used for
a) Sugar coating
b) Film coating
c) Both (a) & (b)
d) None of the above
Ans. : C
14. Subcoating is done to
a) Round the edges
b) Increase in the bulk of tablet
c) Both (a) & (b)
d) Make water resistant
Ans.: C
15. Which one is the example of Opacifier
a) TiO2
b) MgO
c) Silicates
d) None of the above
Ans. : A
16. Empty capsule has moisture content in the range of
a) 60%
b) 12-15%
c) 50-70%
d) 30%
Ans. : C
17. Which machine is designed for filling of pellets?
a) Rotofil
b) Rotosort
c) Ordinary machine
d) None of these
Ans. : A
18. Soft gelatin capsule should not contain more than ____ ppm of iron as impurity?
a) 5
b) 15
c) 40
d) 60
Ans. : B
19. Enteric resin used for coating is?
a) Cellulose acetate Pthalate
b) Zein
c) Shellac
d) All of the above
Ans.: C
20. Base for chewable tablets include
a) Mannitol
b) Glucose
c) Lactose
d) None
Ans. : A
21. Enteric coated tablet disintegrate in
a) Stomach
b) Liver
c) Intestine
d) Mouth
Ans.: C
22. Not used as tablet glidant:
a) Colloidal Silica
b) Starch
c) Talc
d) Magnesium stearate
Ans.: B
23. Rotosort is used for
a) Sorting filled capsules
b) Filling the capsule
c) Mixing of powder
d) None of the above
Ans.: A
24. Hardness of tablet is measured by
a) Pfizer tester
b) Erweka Tester
c) Strong Cobb
d) All of the above
Ans.: D
25. Whiskering (a tablet defect) is observed with the use of _____ punch.
a) Convex
b) Flat
c) Concave
d) Biconvex
Ans.: C
26. Shells of gelatin capsules is made elastic by adding
a) Sorbitol
b) PEG
c) Povidone
d) Lactose
Ans.: A
27. A retardant25. Whiskering (a tablet defect) is observed with the use of _____ punch.
a) Convex
b) Flat
c) Concave
d) Biconvex
Ans.: C
28. How much amount is accepted to dissolve in a dissolution medium in 20 minute at 50 rpm?
a) Not less than 70%
b) Not more than 80%
c) Not less than 80%
d) 80%
Ans.: C
29. What’s the role of cam tracks in tablet compression machines?
a) For proper movement of the punches
b) For proper movement of the granules
c) For proper movement of both (granules and punches)
d) For movement of granules and hopper
Ans.: A
30. Which tablet compression machine is best for compression of granules?
a) Single Press
b) Longitudinal Press
c) Rotary Press
d) Stamping press
Ans.: C
31. Low melting point substances causes processing problem in tablets. Identify it.
a) Poor Flow
b) Weight variation
c) Sticking
d) Picking
Ans.: C
32. Which capsule size number has the maximum capacity?
a) 5
b) 1
c) 0
d) 000
Ans.: D
33. Gelatin and glycerin are used for the preparation of lamellae in a specified ratio. Identify the correct ratio.
a) 1:1
b) 5:1
c) 9:1
d) 10:1
Ans.: C
34. The 000 size capsules can fill the volume of:
a) 1.36 ml
b) 0.13 ml
c) 0.96 ml
d) 0.25 ml
Ans.: A
35. Which of the following material is not used in extrusion?
a) Wax
b) Granules
c) Powders
d) Pellets
Ans.: A
36. What is the name of the phase transition that occurs when a solid is converted directly into a gas (without going through the liquid phase)?
a) Melting
b) Boiling
c) Condensing
d) Sublimation
Ans.: D
37. _______ is used for bulk handling, warehouse storage and transport shipping. The most common form is
a palletized unit load that packs tightly into containers.
a) Primary packaging
b) Tertiary packaging
c) Quaternary packaging
d) Secondary packaging
Ans.: B
38. Packaging Testing includes:
a) Shock test and drop test
b) Vibration test
c) Inclined Impact test
d) All of the above
Ans.: D
39. Disadvantages of plastic material in packaging?
a) Release alkali to aqueous preparation
b) It is fragile so easily broken
c) They react with certain chemicals
d) Absorption permeable to moisture
Ans.: D
40. Iron oxide, magnesium dioxide and chromium dioxide is the composition of ______ colored glass use in pharmaceutical packaging?
a) Yellow
b) Blue
c) Green
d) Amber
Ans.: C
41. Treated Soda lime glass is called as:
a) Type I
b) Type II
c) Type III
d) NP- Non Parentral
Ans.: B
42. Powered glass test used for the standardization of which type of glass material:
a) Type I, II & III
b) Type I, III, IV
c) Type II, III, IV
d) All of the above
Ans.: B
43. Correct test for standardization of rubber material
a) Leakage test/ Collapsibility
b) Powder glass test
c) Fragmentation test
d) Hydraulic test
Ans.: C
44. The main aim of package inserts or leaflets is:
a) To provide information essential for the safe and effective use of the drugs
b) Reducing the number of adverse reactions
c) Adequate direction of use
d) All of the above
Ans.: D
45. “Blue” color coding is used for which class of pharmaceutical products?
a) Miotics
b) Beta blockers
c) NSAIDS
d) Analgesic
Ans.: A
46. “Tan” color coding is used for which class of pharmaceutical products?
a) Miotics
b) Beta blockers
c) NSAIDS
d) Anti infectives
Ans.: D
47. “Orange” color coding is used for which class of pharmaceutical products?
a) Antibiotics
b) Beta blockers
c) NSAIDS
d) Anti-infectives
Ans.: A
48. “Pink” color coding is used for which class of pharmaceutical products?
a) Antibiotics
b) Beta blockers
c) Steroids
d) Anti-infectives
Ans.: A
49. Select the equation that gives the rate of drug dissolution from a tablet:
a) Fick’s Law
b) Henderson-Hasselbatch equation
c) Noyes-Whitney equation
d) Michaelis Menton equation
Ans.: C
50. How many tablets require for content uniformity test
a) 10
b) 20
c) 30
d) 40
Ans.: C
