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pharmacy Topic wise MCQs

PRE-GPAT Preparation MCQs (Part:- 1) with Answers

PRE-GPAT MOCK TEST

1. Effects seen only with depolarizing blockade include all of the following EXCEPT:
a. Hypercaliemia
b. A decrease in intraocular pressure
c. Emesis
d. Muscle pain

2. Correct statements about cortisol (hydrocortisone. include all of the following, EXCEPT:
a. Cortisol is synthesized from cholesterol
b. ACTH governs cortisol secretion
c. Most cortisol is inactivated in the liver
d. The half-life of cortisol in the circulations is normally about 60-90 hours

3. Which neuromuscular blocking agent is contraindicated in patients with glaucoma?
a. Tubocurarine
b. Succinylcholine
c. Pancuronium
d. Gallamine

4. Which of the following glucocorticoids is a short- to medium-acting drug?
a. Prednisolon
b. Dexamethasone
c. Triamcinolone
d. All of the above

5. Which of the following diseases can augment the neuromuscular blockade produced by nondepolarizing musclerelaxants?
a. Myasthenia gravis
b. Burns
c. Asthma
d. Parkinsonism

6. The drug which belongs to nucleoside reverse transcriptase inhibitors:
a. Didanosine
b. Gancyclovir
c. Nevirapine
d. Vidarabine

7. The unwanted effects of zidovudine:
a. Hallucinations, dizziness
b. Anemia, neutropenia, nausea, insomnia
c. Hypertension, vomiting
d. Peripheral neuropathy

8. Indicate the agent, which effectively antagonizes the neuromuscular blockade caused by nondepolarizing drugs:
a. Atropine
b. Neostigmine
c. Acetylcholine
d. Pralidoxime

9. Which of the following sympathomimetics acts indirectly?
a. Epinephrine
b. Norepinephrine
c. Ephedrine
d. Methoxamine

10. Which of the following statements is not correct?
a. ALFA receptors increase arterial resistence, whereas beta receptor promote smooth muscle relaxation
b. The skin and splanchic vessels have predominantly alfa receptors
c. Vessels in a skeletal muscle may constrict or dilate depending on whether alfa or beta receptors are activated
d. Skeletal muscle vessels hav predominantly alfa receptors and constrict in the presence of epinephrine and norepinephrine

11. The group of hormonal drugs used for cancer treatment:
a. Mineralocorticoids and glucocorticoids
b. Glucocorticoids and gonadal hormones
c. Gonadal hormones and somatotropin
d. Insulin

12. Methotrexate is:
a. A purine antagonist
b. A folic acid antagonist
c. An antibiotic
d. An alkylating agent

13. The action mechanism of anticancer drugs belonging to plant alkaloids:
a. Inhibition of DNA-dependent RNA synthesis
b. Cross-linking of DNA
c. Mitotic arrest at a metaphase
d. Nonselective inhibition of aromatases

14. Serious side effects of glucocorticoids include the following, EXCEPT:
a. Acute peptic ulcers
b. Iatrogenic Cushing’s syndrome
c. Salicylism
d. Hypomania or acute psychosis

15. Side effect of cyclosporine A is:
a. Tremor
b. Anorexia
c. Chills
d. Myalgia

16. Beta adrenoreceptor subtypes is contained in all of the following tissues EXCEPT:
a. Bronchial muscles
b. Heart
c. Pupillary dilator muscle
d. Fat cells

17. Which of the following statement is not correct?
A. Αlfa agonists cause miosis
B. Αlfa agonists cause mydriasis
c. Beta antagonists decrease the production of aqueous humor
D. Αlfa agonists increase the outflow of aqueous humor from the eye

18. Drug used for influenza-A prevention
a. Acyclovir
b. Rimantadine
c. Saquinavir
d. Foscarnet

19. A bronchial smooth muscle contains:
a. Alfa 1 receptor
b. Αlfa 2 receptor
c. Beta 1 receptor
d. Beta 2 receptor

20. Enzyme drug used for acute leukemia treatment:
a. Dihydrofolate reductase
b. Asparaginase
c. Aromatase
d. DNA gyrase

21. Which of the following antivitamins prevent a vitamin A from exerting its typical metabolic effects?
a. Lipooxidase
b. Oral contraceptives
c. Antibiotics
d. All of the above

22. Which of the following antienzymes is a proteolysis inhibitor?
a. Contrical
b. Sulbactam
c. Aminocaproic acid
d. Disulfiram

23. All pharmacy colleges conducting degree/diploma in pharmacy has To submitted SIF every year on OR before?
A. 30th August
B. 30th September
C. 1st April
D. None

24. The first pharmacy council of India was constituted by the central Government in
A. 1948
B. 1949
C. 1991
D. 1956

25. Substance specified under which schedule be labeled with the words “Poison: For External Use Only”
A. Schedule G
B. Schedule H
C. Schedule E
D. Schedule P

26. Life period of drug, Ampicillin Sodium” in Cool place is for
A. 12 months B. 24 months
C. 36 months D. 48 months

27. Which color label is used for blood group “O?”
A. Blue
B. Yellow
C. Pink
D. White

28. Prescription related to Narcotic drug has symbol on the top
A. NRx
B. PRx
C. Rx
D. Nx

29. National Institute of Pharmaceutical education and research was first established at
A. Ahmedabad
B. Hyderabad
C. Mohali
D. Guwahati

30. Which section of D & C 1940 related with adulterated drug?
A. 33E
B. 33EE
C. 33D
D. 33G

31. The drug controller general of India is an Ex-officio member of
A. DTAB
B. State Pharmacy council
C. Technical Education Board of State
D. Supreme court of India

32. Provision Applicable To the Production of Bacterial Vaccine Under Which Schedule of D & C Act
A. Schedule E
B. Schedule C1
C. Schedule C
D. Schedule F

33. Haritaki is the Ayurvedic name of
A. Tinospora cordifolia
B. Terminalia belerica
C. Terminelia Arjuna
D. Terminelia chebula

34. One of the following is a “Steroidal Glycoside” as phytoconstituents, it is
A. Quilalia
B. Senna
C. Cascara
D. Digitalis

35. Chemical test for Caffeine is:
A. Keris test
B. Hal-Phens test
C. Murexide test
D. Boarfoeds test

36. Total ash value in the case of crude drug signifies:
A. Organic content of the drug
B. Woody matters present in the drug
C. Mineral matter in the drug
D. All Above

37. Salkowski reaction is used for identify
A. Steroids
B. Tri-terpenes
C. Alkaloids
D. Guggul lipids

38. Which drug is not steroidal saponins?
A. Dioscorea
B. Brahmi
C. Shatavari
D. Gokhru

39. Which one of the following drug does not contain steroidal alkaloid?
A. Kantakari
B. Kada chhal
C. Vacchanag
D. Green hellebore

40. Multiseriate medullary rays and steroidal alkaloids are present in
A. Veratrum
B. Kurchi bark
C. Ashwagandha root
D. Kantakari

41. Creatinine level in urine is analyzed by
A. Hay’s test B. Gmelin test
C. Schiff’s test D. Jaffe’s test

42. Vitiligo is treated by using
A. Embellica officinalis
B. Saraca Indica
C. Azadirachta indica
D. Psoralea corylifolia

43. Rutin is an example of
A. Triterpenoid glycosides
B. Tropane alkaloids
C. Saponin glycoside
D. Flavonoid glycoside

44. Theventia nerrifolia contain
A. Anthraquinone nucleus
B. Flavonol nucleus
C. Steroid nucleus
D. Triterpenoid nucleus

45. Chitin give yellowish brown colour with which reagent?
A. Sudan red
B. chlor zinc chloride
C. alcohol chlorophyll solution
D. iodine solution + sulphuric acid

46. PANAXADIOL is a constituenet of
A. Ginger
B. Paper
C. Ginseng
D. Jatamansi

47. Dragandroff’s reagent doesn’t give a positive test with
A. Emetine
B. Morphine
C. Caffine
D. Codeine

48. In libbermannen Burchard test upper layer shows ____________ colour which shows presence of steroids
A. Red
B. Green
C. Violet
D. Blue

49. Alcohol acts as a clearing agent by dissolving:

  1. A. Gums
  2. B. Mucilage
  3. C. Resins
  4. D. All of above

50. Which solution is commonly known as cuoxam?
A. Copper Dioxide + Ammoniacal solution B. Copper oxide + Silver nitrite solution
C. Copper oxide + Ammoniacal solution
D. None of them

Answers

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