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pharmacy Topic wise MCQs

PRE-GPAT Preparation MCQs (Part:- 7) with Answers

PRE-GPAT MOCK TEST

51. Intrinsic activity found in except
A. Agonist
B. Inverse Agonist
C. Parial agonist
D. Antagonist

52. Atropine does nt inhibit wch secretn?
a.saliva
b.bile
c.tear
d.gi secretn

53. is not a …………chelating agent
a)ethylene diamine
b)tripyridyl
c)EDTA
d)citric acid

54. Oral bioavailability of griseofulvin is increased by
A. Micronization
B. Solid dispersion
C. Amorphous generation
D. None

55. ROTOSORT capsule sorting machine has max. Handling of……capsules/hr?
a.1500
b.15000
c.150000
d.100000

56. All of the following hormones have cell surface receptors except
a. Adrenaline
b. GH
c. Insulin
d. Thyroxine

57. Bancroft rule is related with
a. Solutions
b. Suspensions
c. Emulsions
d. Suppositories

58. In lyophilized sterile powders Trihydroxy methyl amino methane is used as?
A) Buffer
B) bulking agents
C) Protectant
D) None of the above

59. Defect in philiadephia chromosomes lead to
A. Leukaemia
B. Anaemia
C. Thrombocytosis
D. Lymphocytosis

60. Which company is launching generic version of lipitor in india after pfizer lost it patentship on november 30,2011 in USA?
a. Glaxosmith
b. Cadila
c. Ranbaxy
d. Dr.Reddys

61. Sulfonamides are metabolised by humans principally by
A. Acetylation
B. Deamination
C. Oxidation
D. Conjugation

62. Rotation of electrons about the proton generates a secondary magnetic field which may oppose the applied field the, the proton is said to be
A.shielded
B.shifted
C.deshielded
D.bonded

63. The chemical shift in NMR is expressed in
A.parts per million
B.gauss
C.tesla
D.hertz

64. Saturable transport systems?
a)passive diffusion
B) aqueous diffusion
C) lipid diffusion
D) active transport — carrier mediated

65. which of the following is a diuretic steroid
a.acetazolamide
b.furosemide
c.spiranolactone
d.both a & c

66. Gossypol is…………
a)Hormone b) Pigment
c)Enzyme d)All of these

67. the solubility of the drug will be high when it in its
a) stable form
b)metastable form
c)unstable form
d) all of the above

68. angle of repose of given powder is between 30-40 degree the type of flow is
a) excellent b) good
c) passable d) very poor

69. which of the following is an active from of cocaine
a) Ecgonine
b)Tropococaine
c)Atropine
d)Pseudo cocaine

70. IR radiation source, globar is chemically
a. silicon carbide
b. silicon disulfide
c. zirconium oxide
d. thorium

71. The deflection of positive ions formed in a mass spectrometer by electric and magnetic field depends upon its
a.mass
b.velocity
c.charge
d.all of the above

72. The most intense peak in mass spectrum is known as
a.base peak
b.metastable peak
c.rearrangement peak
d.molecular ion peak

73. A compound will be sensitive towards IR radiations only when one of the following properties undergo transition
a. polarisability
b. Dielectric constant
c. dipole moment
d. refractivity

74. Widely used recorder in mass spectrophotometer is
a. thermocouple
b. galvanometer
c. photomultiplier tube
d, photocell

75. Munsell system is associated with?
a, odor
b. flavor
c. color
d. chemical classification

76. reagent gas used in chemical ionisation
a. methane b. isobutane
c. ammonia d. all the above

77. the molecular weight of compound in mass spectrum is
a.highest m/e value in mass spectrum
b.lowest m/e value in mass spectrum
c.the intensity which is equal to 100%
d. none

78. The characteristic odour of garlic is due to
A) a chloro compound
B) a sulphur compound
C) a fluorine compound
D) acetic acid

79. the product of fragmentation in mass spectroscopy
a. may be radical cation
b. may be cation
c. may be radical
d. all the above

80. Imipenem is inactivated by dehydro peptidase in renal tubules, belongs to class
a) Penicillin
b) Cephalosporine
c) Monobactum
d) Carbapenem

81. Which electronic transition requires maximum energy?
A) pie-pie*
B) n-pie*
C) sigma-sigma*
D) n-n*

82. The digitalis action is enhanced by
a)sodium
b)calcium
c)magnesium
d)potassium

83. Limonene is synthesized from?
a. terpeniol
b. citral
c. ionone
d. dipentene

84. PEG 4000 monostearate is not miscible with?
a. Water
b. Alcohol
c. Ether
d. Benzene

85. Betadine contains?
a.benzocaine
b.surfacaine
c.povidone iodine complex
d.gentian violet

86. Lente insulin is?
a. givn only iv
b. another name for NPH insulin
c. 70percent crystalline, 30percent amorphous
d. 70percent amorphous, 30 percent crystalline

87. Rhubarb contain ______ type of glycoside
A. C-Glycoside
B. O-Glycoside
C. S-Glycoside
D. N-Glycoside

88. which drug has pappilose cells?
a.cocaleaf
b.punarnava
c.shankhpushpi
d.digitalis

89. A mosquito repellent volatile oil is obtained from
a) Artemisia brevifolia
b) Cymbopogonnardus
c) Trachys permumammi
d) Cymbopogon flexuosus

90. which of d these should not be administered to a patient with myasthenia gravis?
a)physostigmine
b)digitalis
c)atropine
d)curare

91. The metabolic function of riboflavin involves ?
a.FMN and FAD
b. NADP and NADPH
c. AMP and ATP
d. Retin and retinine

92. Which water is used 4 hand washing in change room of p’ceutical manufacturing plant?
A Potable B Purified
C Disinfectant D Soap

93. A metabolite of spironolactone?
a. Pregnenolone
b. Corticosterone
c. Canrenone
d. Aldosterone

94. wich of d following is neurotoxin
a-tetanus
b-vibrio
c-tubercullin
d-tetanospasmin

95. klung test is for
a-aloesin
b-isobarbaloin
c-barbaloin
d-aloe-emodin

96. idioblast r present in ?
a- cinchona
b-coca
c-hyoscyamus
d- all

97. Who is new owner of piramal healthcare?
a. Adobbt
b. Pfizer
c. Glaxosmith
d.Merck

98. Which of d fllwing antidepressant is safe in overdose?
A. Venlafaxine
B. Trazodone
C. Reboxetine
D. All the above

99. Digeorage’s syndrome is a?
a. Related to males, characterized by failure of conversion of b-lymphocytes into antibody producing plasma cells
b. failure of thymus to develop diminished T cell response
c. All the above
d. None of the above

100. If I have a cold, food may not taste as good to me because
A) The nerve fibrils are not functioning properly
B) My food will taste the same; taste and smell have nothing in common
C) Papilla become blocked by mucus and are unable to function
D) Olfaction, taste and trigeminal receptors together contribute to the flavor of my food

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