Discription
Physical pharmacutics
Unit:- 1
(Solubility of drugs)
- Definition:- solutions , solubility
- Types of solutions
- Solubility expression
- Mechanism of solut solvent interaction
- Ideal solubility parameters
- Write details note about solutions
- Define Association
- Factors affecting of solubility
- Binary solutions
- Ideal or non ideal solution
- Details short note about roults law , Henry law,
- Pashal pressure, distribution laws (partition conficient)
- How we seperate drugs in oil phase with water phase (separation method)
According syllabus
UNIT-I
- Solubility of drugs: Solubility expressions, mechanisms of solute solvent interactions,
- ideal solubility parameters, solvation & association, quantitative approach to the factors
- influencing solubility of drugs, diffusion principles in biological systems. Solubility of gas in liquids, solubility of liquids in liquids, (Binary solutions, ideal solutions)
- Raoult’s law, real solutions. Partially miscible liquids, Critical solution temperature and applications. Distribution law, its limitations and applications
- Differentiate between a saturated and supersaturated solution. Explain the solute solvent interactions for polar and nonpolar solvents.
