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Solubility of drugs full details pdf study material


Physical pharmacutics

Unit:- 1
(Solubility of drugs)

  • Definition:- solutions , solubility
  • Types of solutions
  • Solubility expression
  • Mechanism of solut solvent interaction
  • Ideal solubility parameters
  • Write details note about solutions
  • Define Association
  • Factors affecting of solubility
  • Binary solutions
  • Ideal or non ideal solution
  • Details short note about roults law , Henry law,
  • Pashal pressure, distribution laws (partition conficient)
  • How we seperate drugs in oil phase with water phase (separation method)

According syllabus


  • Solubility of drugs: Solubility expressions, mechanisms of solute solvent interactions,
  • ideal solubility parameters, solvation & association, quantitative approach to the factors
  • influencing solubility of drugs, diffusion principles in biological systems. Solubility of gas in liquids, solubility of liquids in liquids, (Binary solutions, ideal solutions)
  • Raoult’s law, real solutions. Partially miscible liquids, Critical solution temperature and applications. Distribution law, its limitations and applications
  • Differentiate between a saturated and supersaturated solution. Explain the solute solvent interactions for polar and nonpolar solvents.