Dose-Response Relationship (DRR) When the relation between drug dose (X-axis) and drug response (Y-axis) is plotted on a linear scale, the resulting curve is usually...
JAK-STAT Binding Receptor Janus kinase (JAK) is a family of intracellular nonreceptor tyrosine kinases which transduce cytokine-mediated signals via the JAK-STAT pathway. They were initially...
Ion-channel Receptors Ion channels are pore-forming membrane proteins which allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential,...
G-protein Coupled Receptors G-protein coupled receptors (GPCRs) represent the largest family of membrane proteins in the human genome. It is one of the richest sources...
Signal Transduction Mechanisms Signal transduction is the process in which a chemical or physical signal is transmitted through a cell as a series of molecular...
Drug-Receptor Interaction The idea that drug molecules interact at specific sites in the body is a relatively old concept. However, proof of the receptor concept...
Classification of Receptors Receptors are glycoproteins located in cell membranes which specifically recognise and bind to ligands/drugs. Drugs are smaller molecules which are capable of...
Receptors Regulating Transcription Factors       A transcription factor (TF) or sequence-specific DNA-binding factor is a protein which controls the rate of...
Trans-Membrane Linked Receptors        An enzyme linked-receptor, also known as catalytic receptor, is a transmembrane receptor, where the binding of...
hello viewrs in this video we gonna know about the asthmatic Drugs specialllu sub class of LEUKOTRIENE ANTAGONIST Asthma means it is disorder of the...
Receptor Theories Discuss theories of drug receptor interaction There are three major theories for drug-receptor interaction. They are as follows: (i) Occupation theory Occupation theory...
Principles and Mechanisms of Drug Action Principles Drugs do not create any new functions to any physiological system but can only increase, decrease or replace...
PHARMACEUTICAL WAREHOUSING INTRODUCTION: • Maintaining proper storage condition for pharmaceutical products and paramedical is vital to ensure their quality, safety and efficacy. • Factory stores...