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pharmacy Topic wise MCQs

Pharmaceutics (Part-3 ) MCQs with Answers

PHARMACEUTICS

1. The ability of a substance dissolves in a given solvent system is depends on
(a) Nature and intensity of the forces present in the solute
(b) Nature and intensity of the forces present in the solvent
(c) Interactions between solute and solvent
(d) All the above

2. Which of the following substances having poor water solubility
(a) Weak electrolytes
(b) Non-polar molecules
(c) Both
(d) None

3. The solubility of weak electrolytes & non-polar substances can be increased by adding water miscible solvents. This process is known as
(a) Co-solvency
(b) Complexation
(c) Both
(d) None

4. How co-solvents increase the solubility of poorly soluble drugs?
(a) By reducing the interfacial tension between the predominant aqueous solution and hydro-phobic solute
(b) By reducing the interfacial tension between solute and solvent
(c) Both
(d) None

5. Which of these co – solvents are used to increase the solubility of a drug
(a) Ethanol
(b) Sorbitol
(c) Glycerin
(d) All the above

6. Which of these co – solvent is accepted as a co – solvent in parenteral products, but its use in oral liquids is limited
(a) Glycerol formal
(b) Glycerol
(c) Dimethyl acetamide
(d) None

7. Due to which factor, dimethyl acetamide is not been used as a co-solvent in oral liquids
(a) Due to objectionable odor
(b) Due to objectionable taste
(c) Both
(d) None

8. Thiomersal is belongs to which category preservative
(a) Acidic
(b) Neutral
(c) Mercurial
(d) Quaternary ammonium compounds

9. Which of the following are widely used and excellent preservatives
(a) Mercurial
(b) Quaternary ammonium compounds
(c) Both
(d) Acidic

10. Benzalkonium chloride is categorized as
(a) Acidic preservative
(b) Neutral preservative
(c) Mercurial preservative
(d) Quaternary ammonium compounds

11. At which concentration, phenol act as preservative
(a) 0.2 – 0.5%
(b) 0.5 – 0.8%
(c) 0.05 – 0.1%
(d) None

12. Which of the following sugar has bitter taste
(a) Glucose
(b) Sucrose
(c) Saccharine
(d) None

13. Which of the following is a synthetic sweetener
(a) Glucose
(b) Sucrose
(c) Sorbitol
(d) Aspartame

14. To increase the viscosity of liquid, which of the following agents are used
(a) PVP
(b) Methyl Cellulose
(c) Sodium Carboxy Methyl Cellulose
(d) All the above

15. Which of the following agents are used as flavoring agents
(a) Menthol
(b) Chloroform
(c) Both
(d) None

16. Most widely used flavoring agent in food industry
(a) Menthol
(b) Chloroform
(c) Mono sodium glutamate
(d) None

17. Which of the following flavor is not responsible for sour taste
(a) Citrus flavors
(b) Liquorice
(c) Raspberry
(d) Mint spice

18. The filling method of a pharmaceutical liquid depends on the following factors
(a) Viscosity of the liquid
(b) Surface tension of the liquid
(c) Compatibility with the materials used in the construction of the filling machine
(d) All the above

19. Which of the following methods are generally used in liquid filling
(a) Gravimetric
(b) Volumetric
(c) Constant level method
(d) All the above

20. In the formulation of suspensions, generally which types of drugs are selected?
(a) Hydrophilic (b) Hydrophobic
(c) Both (d) None

21. In the formulation, to facilitate the wetting of insoluble solids, which of the following agents used
(a) Suspending agents
(b) Flavoring agents
(c) Wetting agents
(d) None

22. How surfactants will facilitate or aid wetting of hydrophobic materials in liquid
(a) By decreasing the solid-liquid interfacial tension
(b) By increasing the solid-liquid interfacial tension
(c) Both
(d) None

23. Stoke’s equation is expressed as

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(c) Both
(d) None

24. The stability of suspensions can be evaluated by
(a) Sedimentation volume
(b) Degree of flocculation
(c) Re-dispersibility
(d) All

25. To identify the emulsion type, which of the following tests are conducted?
(a) Dilution test
(b) Dye test
(c) Conductivity test
(d) All

26. The temperature at which the inversion occurs depends on emulsifier concentration is known as
(a) Phage temperature
(b) Inversion temperature
(c) Phase inversion temperature
(d) All

27. Which of the following mechanical equipment can be used for emulsification?
(a) Homogenizers
(b) Mechanical stirrers
(c) Ultra sonifiers
(d) All

28. Which of the following is not used as an emulsifying agent?
(a) Surfactant
(b) Hydrophilic colloids
(c) Electrolytes
(d) Finely divided solids

29. HLB system was developed by
(a) Griffin
(b) Stock’s
(c) Dalla Valle
(d) None

30. Gum Arabic is a
(a) Anionic polysaccharide
(b) Cationic polysaccharide
(c) Neutral polysaccharide
(d) None

31. Which of the following is not a Semi solid dosage form
(a) Paste
(b) Creams
(c) Ointments
(d) Suspensions

32. Generally pastes contain
(a) High percentage of insoluble solids
(b) Low percentage of insoluble solids
(c) Both
(d) None

33. Most widely used hydrocarbon in Semi-solid dosage forms
(a) Petrolatum
(b) Mineral oil
(c) Both
(d) None

34. Which of the following hydrocarbon waxes are employed in the manufacture of creams and ointments?
(a) Paraffin wax
(b) Ceresin
(c) Both
(d) None

35. Which of the following is not a vegetable oil
(a) Peanut oil
(b) Almond oil
(c) Olive oil
(d) Petrolatum

36. Which of the following fatty acid used in water removable creams as emulsifier
(a) Stearic acid
(b) Palmitic acid
(c) Both
(d) None

37. Combination of a surfactant with oilsoluble auxiliary emulsifier is known as
(a) Simple emulsifier system
(b) Mixed emulsifier system
(c) Both
(d) None

38. Promulgen means
(a) Anionic emulsifiers composed of fatty alcohols & their ethoxylates
(b) Non-ionic emulsifiers com-posed of fatty alcohols & their ethoxylates
(c) Cationic emulsifiers composed of fatty alcohols & their ethoxylates
(d) All the above

39. Promulgen D contains
(a) Cetyl alcohol & Ceteareth-20
(b) Stearyl alcohol & Ceteareth-20
(c) Both
(d) None

40. Promulgen G contains
(a) Cetyl alcohol & Ceteareth-20
(b) Stearyl alcohol & Ceteareth-20
(c) Both
(d) None

41. With promulgen D, which type of emulsion generally obtained?
(a) Liquid emulsion
(b) Thick consistency emulsion
(c) Both
(d) None

42. With promulgen G, which type of emulsion generally obtained?
(a) Liquid emulsion
(b) Thick consistency emulsion
(c) Both
(d) None

43. Which of the following polyols used as humectants in creams
(a) Glycerine
(b) Propylene glycol
(c) Sorbitol 70%
(d) All the above

44. The choice of humectants is based on
(a) Rate of moisture exchange
(b) Viscosity and texture of preparation
(c) Both
(d) None

45. Which of the following is more hygroscopic at low concentration?
(a) Sorbitol 70%
(b) Glycerine
(c) Both
(d) None

46. Due to which factors, petrolatum is most widely used as a hydrocarbon basic in ointments
(a) Its consistency
(b) Its neutral characteristics
(c) Its ability to spread easily on the skin
(d) All

47. Water number means
(a) Maximum amount of water that can be added to 100 g of a base at given temperature
(b) Maximum amount of water that can be added to 10 g of a base at given temperature
(c) Maximum amount of water that can be added to 5 g of a base at given temperature
(d) All

48. Lanolin is which type of base
(a) Hydrocarbon base
(b) Absorption base
(c) Both
(d) None

49. In the preparation of vanishing creams, which types of bases are used generally?
(a) Absorption bases
(b) Water removable bases
(c) Hydrocarbon bases
(d) None

50. In the preparation of cold creams, which types of bases are used generally?
(a) Absorption bases
(b) Water removable bases
(c) Hydrocarbon bases
(d) None

Answers

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