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pharmacy Topic wise MCQs

Pharmaceutics (Part-6) MCQs with Answers

PHARMACEUTICS

51. Sta-Rx-1500 contains…% of moisture
(a) 15
(b) 10
(c) 18
(d) 50

52. Acacia trgacanth is used in the concentration of
(a) 10%-25 %
(b) 60%-70 %
(c) 40%-50 %
(d) 90%

53. Starch on heating hydrolyze into
(a) Glucose
(b) Fructose & Sorbose
(c) Fructose & Mannose
(d) Dextrin & Glucose

54. pH of the small intestine is
(a) 1-2
(b) 3-4
(c) 6
(d) 7-8

55. Aqua coat is a
(a) 30% w/v of ethyl cellulose dispersion
(b) Solution of HPMC
(c) 2% w/v of methyl cellulose dispersion
(d) None

56. Lozenges were originally named as
(a) Capsule
(b) ODT
(c) Pastillies
(d) Sustained release tab

57. Implantation tab are NMT……..mm in length
(a) 20
(b) 100
(c) 40
(d) 8

58. Seal coating is done by using
(a) Shellac
(b) Acacia
(c) Gelatin
(d) None

59. Sub coating is done to
(a) Round the edges
(b) Increase the bulk of tablet
(c) Both a & b
(d) Make water resistant

60. CAP dissolves at PH
(a) Above 6
(b) Below 6
(c) 4
(d) 2

61. Which of the following one is used as opacifier
(a) TiO2
(b) Mgo
(c) Siliactes
(d) All of the above

62. Green bone is a source of
(a) Type A Gelatin
(b) Type B Gelatin
(c) Both
(d) None

63. Empty capsule has moisture content in the range of
(a) 60%
(b) 12%-15 %
(c) 50%- 70%
(d) 30%

64. Which treatment is used for solubility of gelatin?
(a) Heat
(b) Formalin
(c) Water
(d) Alcohol

65. Which of the following is used to fill powdered dry solid into soft gelatin capsule
(a) Aceogel
(b) Rotobil
(c) Rotosort
(d) Rotoweigh

66. Sealing of capsule is achieved by
(a) 100oC
(b) 20oC
(c) 37oC-40oC
(d) 70oC

67. Moisture content is determined by
(a) Gas Chromatography
(b) K-F Method
(c) Both
(d) None

68. Foam stability is measured by
(a) IR Spectroscopy
(b) UV Spectroscopy
(c) Rotational viscometers
(d) All

69. Particle size is determined by
(a) Gas Chromatography
(b) Cascade impactor
(c) Light scatter decay
(d) Both b & c

70. Chewable tablet contains these base
(a) Manitol
(b) Glucose
(c) Lactose
(d) None

71. Which of the following is not added in lozenges?
(a) Sweetener
(b) Binder
(c) Disintegrant
(d) All

72. Enteric coated tablet is disintegrated in
(a) Stomach
(b) Liver
(c) Intestine
(d) Mouth

73. Which drug is formulated as first pharmaceutical aerosol?
(a) Epinephrine
(b) Codeine
(c) Chloropromazine
(d) Probenecid

74. To dispense inhalation aerosols, which containers are used?
(a) Stain less steel containers
(b) Tin plate containers
(c) Glass containers
(d) Al containers

75. The valve body /housing in an aerosol bottle valve assembly, is made from one of the following
(a) Nylon
(b) Poly propylene
(c) Poly ethylene
(d) Stain less steel

76. The equipment listed P-T is used for the identification of properties of aerosol mentioned below. Match them.
1. Particle size determination
2. Identification of propellants
3. Stability of foam
4. Flash point
(P) Pycnometer
(Q) Rotaional viscometer
(R) Tag open cap apparatus
(S) IR spectroscopy
(T) Cascade impaction
(a) 1-P, 2-Q, 3-R, 4-S
(b) 1-Q, 2-P, 3-S, 4-T
(c) 1-T, 2-S, 3-Q, 4-R
(d) 1-R, 2-S, 3-P, 4-Q

77. pH of human tear is
(a) 7.2
(b) 8
(c) 7.6
(d) 4.6

78. Match the coatings given below with their corresponding techniques listed P-T
1. Compression coating
2. Dip coating
3. Electrostatic coating
4. Vacuum film coating
(P) Air in the coating pan is replaced with Nitrogen
(Q) Application of coating to conductive substrates
(R) Acid insoluble coating
(S) A tablet within a tablet
(T) Replaced coating & drying
(a) 1-S, 2-R, 3-Q, 4-P
(b) 1-Q, 2-R, 3-S, 4-T
(c) 1-P, 2-R, 3-T, 4-S
(d) 1-R, 2-T, 3-P, 4-Q

79. Among the propellants used in aerosols, one of the following is used for topical pharmaceutical aerosols
(a) Tri chloro monofluoro methane
(b) Di chloro difluoro methane
(c) Di chloro tetrafluoro ethane
(d) Propane

80. Which one of the following propellant is used in the aerosol for oral use?
(a) Propane
(b) Oxygen
(c) Methane
(d) Trichloro monofluoro methane

81. The identification of propellants in pharmaceutical aerosols is carried out by
(P) Gas chromatography
(R) Pycnometer
(Q) Tag open cup apparatus
(S) IR spectrophotometer
(a) P, Q
(b) P, S
(c) Q, R
(d) R, S

82. Aerosol packaging container must resist pressure of
(a) 500 psig
(b) 140-180 psig
(c) 40 psig
(d) 20 psig

83. Gasket is made up of
(a) Buna-N
(b) Neoprene rubber
(c) Both
(d) All

84. Manufacturing of aerosol involves
(a) Gas filling
(b) Pressure filling
(c) Cold filling
(d) All the above

85. The nature of propellant is determined by
(a) R-F method
(b) Gas Chromatography
(c) UV
(d) None

86. Viscosity enhancer in ophthalmic preparation is
(a) Poly vinyl alcohol
(b) Povidone
(c) Dextran
(d) Macrogol

87. Opthalmic solution is sterilized by
(a) Autoclave
(b) Hot air oven
(c) Both
(d) Bacterial filters

88. How many parts of 10 % ointment be mixed with 2 parts of 15 % ointment to get 12% ointment?
a) 2
b) 3
c) 5
d) 6

89. The correct non-ionic surfactant used as a penetration enhancer in the preparation of mucoadhasives
a) Oleic acid
b) Tween-80
c) Glycerol
d) Propylene glycol

90. A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is
a) H.P.M.C
b) C.A.P
c) Polyethylene
d) Carnauba wax

91. ENO is the example of?
A. Effervescent granules
B. Dry sealed sachet
C. tablet triturate
D. powder

92. Plasticizers use in coating solution is?
A. Polyethylene glycol
B. castor oil
C. propylene glycol
D. all above

93. The efficiency of witting agents is measured by
a) DOP test
b) Draves test
c) Carr’s index
d) Dock test

94. Which one of the following coating material is used for sub coating?
a) HPMC
b) Carnauba wax
c) Gelatin
d) PEG-4000

95. Sodium starch glycollate is used as
a) Glidant
b) Lubricant
c) Disintigrant
d) Binder

96. Which one tablet does not require disintegrant?
a) Effervesant
b) Sublingual
c) Dissolution tab
d) Buccal

97. The most commonly used humectants in tooth paste includes
a) Glycerol
b) Sorbitol
c) Both a & b
d) None of these

98. Green color frequently used in eye makeup preparation is
a) Carmine
b) Iron oxide
c) Chromium oxide
d) Mascara

99. The HLB value of sodium oleate is
a) Approx 3.0
b) Around 10.0
c) Around 18.0
d) Approx 40.0

100. Basket dissolution apparatus is
a) USP dissolution apparatus 1
b) USP dissolution apparatus 2
c) USP dissolution apparatus 3
d) USP dissolution apparatus 4