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Pharmacognosy 2 GTU Exam IMP/ Commen Question

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   1. 1. Metabolic pathways in higher plants and their determination
WINTER -2019
   1. Explain Shikimic acid pathway with chemistry. 06
   2. (b) Write in detail about acetate mevalonate pathway. 05
   3. (c) Discuss in detail about the pathway for biosynthesis of lipids in plants.
   4. Write down different methods of tracer techniques in the investigation of
      Biogenetic studies.
SUMMER -2020
   1. Write a short note on Radioactive isotopes in the investigation of Biogenetic Studies.
   2. (b) Describe the Shikimic acid pathway. 05
   3. (c) Write a note on Acetate mevalonate pathway.
WINTER -2020
   1. Write a detailed note on use of types of radioisotopes and their characteristics
      in biogenetic studies. 06
   2. (b) Write the biogenetic pathway of amino acids.
   3. Write a detailed note on methods used to apply/feed radioactive substances to
      plants during biogenetic studies.
SUMMER -2021
   1. Enumerate basic metabolic pathways and write in brief the formation of aromatic amino
      acids.
   2. Write the methods by which radioactive isotopes are used in the study of biogenetic
      studies.
   3. Give a list of secondary metabolites synthesized through acetate pathways. Write the
      pathway of any one.
   4. How are radioactive isotopes fed to the plants for the study of biogenetic pathways?

2. General introduction, composition, chemistry & chemical classes, biosources,
therapeutic uses and commercial applications of following secondary metabolites:
WINTER -2019
1. Define Alkaloids. Write down its classification with examples. 06
2. (b) Write down source, chemical constituents and uses of Rauwolfia and Opium. 05
3. (c) Write down source, chemical constituents and uses of Colophony and Ginger. 05
4. Define Tannins and Glycosides. Write down chemical constituents and uses of
Asafoetida and Taxus. 06
5. (b) Differentiate between Fennel and Coriander.
6. Write down pharmacognosy of a drug used as a dental analgesic.
7. Differentiate between Pale catechu and Black catechu.
SUMMER -2020
1. Define Resins. Write a short note on Ginger. 05
2. (c) Write biological source, family, chemical constituents and uses of Benzoin and clove.
3. Write a short note on Narcotic preparation of Opium.
4. Differentiate between Black catechu and Pale catechu. 06
5. (b) Give a detailed note on anti-cancer drugs. 05
6. (c) Write biological source, family, chemical constituents and uses of Taxus and Gentian.
7. Give detail note on pharmacognosy on Senna. 06
8. (b) What are different sources of Aloe? Explain their method of preparation. 05
9. (c) Draw a well labeled morphology and microscopical diagram (T.S) of Fennel.
WINTER -2020
1. Write the sources and types of alkaloids present in rauwolfia.
2. Write a note on glycosides present in dioscorea. Explain with the help of
reactions the commercial application of diosgenin. 06
3. (b) Write a note on the general introduction of glycosides. Differentiate between types
of cardiac glycosides. 05
4. (c) Write chemistry, sources and uses of guggul.
5. Write the chemistry, composition and commercial application of alkaloids
present in belladonna.06
6. Write a note on the chemistry of alkaloids present in opium. 06
7. Write a note on chemical classification of flavonoids. Write the commercial
application of rutin.06
SUMMER -2021
1. Write the chemical test for identification of indole alkaloid. Write a note on
chemical constituents and uses of Rauwolfia.
2. Write the biological source, chemical composition and therapeutic uses of guggul.
3. What are iridoids? Write the biological sources and chemical constituents of gentian.
4. Write a note on chemical constituents of licorice.
5. Write a note on biological sources, chemical constituents and uses of clove.

3. Isolation, Identification and Analysis of Phytoconstituents
WINTER -2019
1. Give a method for isolation and estimation of Caffeine.
2. Write the biological source, isolation and estimation method of Podophyllotoxin.
3. Write a method for isolation of atropine and Curcumin.
4. Write down isolation, identification and analysis of Menthol. 05
5. (c) Give the source, isolation and identification method of Glycyrrhetinic acid.
SUMMER -2020
1. Write on sources, isolation and identification of Curcumin. 06
2. Write on sources, isolation and identification of Quinine.
3. Write on sources, isolation and identification of Rutin. 06
WINTER -2020
1. Write the method of isolation and analysis of menthol.
2. Write isolation, identification and analysis of artemisinin. 06
3. (b) Write isolation, identification and analysis of glycyrrhetinic acid 05
4. (c) Write isolation, identification and analysis of quinine.
SUMMER -2021
1. Which method is used for analysis of quinine? Explain the same in detail.
2. How is menthol isolated? Write a detailed note on it.
3. What are resins? Write the isolation of curcumin.
4. Industrial production, estimation and utilization of the following phytoconstituents:
WINTER -2019
1. Describe a suitable method for production and estimation of Diosgenin.
2. Write a note on production and estimation of Sennosides.
SUMMER -2020
1. (b) Brief note on estimation and utilization of Digoxin. 05
2. (c) Describe in detail on production and estimation of Vincristine.
3. (b) Brief note on estimation and utilization of Sennoside. 05
4. (c) Write on industrial production and estimation of Caffeine.
WINTER -2020
1. Write industrial production and utilization of caffeine.
2. Write the industrial production and utilization of vincristine and vinblastine. 06
3. (b) Write estimation and utilization of sennosides. 05
4. (c) Write industrial production method and estimation method of forskolin.
SUMMER -2021
1. How is industrial production of podophyllotoxin carried out? Write utilization
of podophyllotoxin.
2. Which are the methods used for estimation of digoxin? Explain in detail.
3. Give a detailed note on industrial production of vincristine and vinblastine.
4. Give a detailed account of the method of estimation of taxol and write its uses.
5. Write the estimation and uses of atropine.

5. Basics of Phytochemistry
WINTER -2019
1. Define extraction. Enlist different modern methods of extraction. Explain in detail
Microwave assisted extraction. 06
2. (b) Give significance of HPTLC and GC in isolation, purification and identification
of crude drugs.05
3. (c) Write a note on supercritical fluid (SCF) extraction.
SUMMER -2020
1. Enlist modern methods of extraction. Describe electrophoresis in detail. 06
2. (b) Describe the steam distillation method with a well labeled diagram.
WINTER -2020
1. Explain the terms extraction and isolation with the help of examples. Enumerate
methods of extraction. 06
2. (b) Write the application of latest spectroscopic techniques in Phytochemistry. 05
3. (c) Write a note on application of HPTLC-MS technique in identification of
Phytoconstituents.

SUMMER -2021
1. Enlist method of extraction. Explain continuous extraction method with
diagram.
2. Classify chromatographic techniques used for isolation. Write in brief about
any one technique.
3. Write a detailed note on UV – Spectroscopic method for identification of
phytoconstituents.
4. Write a note on electrophoresis used for isolation, purification and identification
of crude drugs.

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Subject:
Pharmacognosy 2
Semester:
Sem 5
Cource:
Bachelor of Pharmacy

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